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Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (AA 23-53), (N-Term) antibody

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Synonyms Neb2, PPP1R6, PPP1R9, SPINO, Spn, SPL
N-Term, AA 23-53
(17), (15), (13), (3), (3), (2), (2), (1), (1)
(44), (21), (18)
(44), (2), (1)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(33), (18), (11), (4), (3), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of Human Neurabin-2. Genename: PPP1R9B
Isotype Ig
Specificity This antibody recognizes Human Neurabin-2 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Neurabin-2 (PPP1R9B Antibody Abstract)
Background Spinophilin is a regulatory subunit of protein phosphatase-1 catalytic subunit (PP1, see MIM 176875) and is highly enriched in dendritic spines, specialized protrusions from dendritic shafts that receive most of the excitatory input in the central nervous system (Allen et al., 1997 [PubMed 9275233]).Synonyms: Neurabin-II, PPP1R6, PPP1R9B, Protein phosphatase 1 regulatory subunit 9B, Spinophilin
Molecular Weight 89192 Da
Gene ID 84687
NCBI Accession NP_115984
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Protein Phosphatase 1, Regulatory Subunit 9B, Spinophilin (PPP1R9B) (AA 23-53), (N-Term) antibody (ABIN953658) Western blot analysis of Neurabin-2 Antibody (N-term) in Ramos cell line lysates (35u...
Background publications Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Rajagopal, Ji, Xu et al.: "Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1)." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 18060-71, 2010 (PubMed).

Martins-de-Souza, Gattaz, Schmitt et al.: "Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia." in: European archives of psychiatry and clinical neuroscience, Vol. 259, Issue 3, pp. 151-63, 2009 (PubMed).

Sagara, Kawasaki, Iemura et al.: "Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration." in: Oncogene, Vol. 28, Issue 10, pp. 1357-65, 2009 (PubMed).

Meng, Kanwar, Du et al.: "PPP1R9B (Neurabin 2): involvement and dynamics in the NK immunological synapse." in: European journal of immunology, Vol. 39, Issue 2, pp. 552-60, 2009 (PubMed).

Catalog No. ABIN953658
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