Phosphatase and Actin Regulator 4 (PHACTR4) (C-Term), (AA 543-572) antibody

Details for Product No. ABIN954113
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Synonyms 3110001B12Rik, AI527228, AW495572, C330013F19Rik, N28169, mKIAA4120, phactr4, zgc:63484, MGC151764, DKFZp469H1423
C-Term, AA 543-572
(6), (2), (1), (1), (1)
Human, Mouse (Murine)
(18), (2), (2)
ELISA, Western Blotting (WB)
(18), (15), (5)
Pubmed 5 references available
Catalog no. ABIN954113
Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 543~572 amino acids from the C-terminal region of human PHCTAR4
Specificity This antibody recognizes Human and Mouse PHACTRA (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PHACTR4
Background This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternate names: PRO2963, Phosphatase and actin regulator 4
Molecular Weight 78211 Da
Gene ID 65979
NCBI Accession NP_001041648
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Sagara, Higuchi, Hattori et al.: "Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure." in: The Journal of biological chemistry, Vol. 278, Issue 46, pp. 45611-9, 2003 (PubMed).

Allen, Greenfield, Svenningsson et al.: "Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 18, pp. 7187-92, 2004 (PubMed).

Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Hosts (18)
Reactivities (18), (2), (2)
Applications (18), (15), (5)
Epitopes (6), (2), (1), (1), (1)
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