Polycystic Kidney Disease 2-Like 1 (PKD2L1) (N-Term), (AA 36-65) antibody

Details for Product No. ABIN954156
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms PKD2L1, si:packtrz.2, si:xx-packtrz.2, B830002B15, BC046386, PCL, PKD2L, Pkdl, TRPP3, PKDL
N-Term, AA 36-65
(16), (14), (2), (2), (1), (1), (1), (1), (1)
(26), (5), (3)
(27), (2)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(29), (17), (3), (3), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954156
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human PKD2L1
Isotype Ig
Specificity This antibody recognizes Human PKD2L1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PKD2L1
Background PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.Synonyms: PKD2L, PKDL, Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1
Molecular Weight 91982 Da
Gene ID 9033
NCBI Accession NP_057196
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Molland, Narayanan, Burgner et al.: "Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2." in: The Biochemical journal, Vol. 429, Issue 1, pp. 171-83, 2010 (PubMed).

Kawaguchi, Yamanaka, Uchida et al.: "Activation of polycystic kidney disease-2-like 1 (PKD2L1)-PKD1L3 complex by acid in mouse taste cells." in: The Journal of biological chemistry, Vol. 285, Issue 23, pp. 17277-81, 2010 (PubMed).

Li, Dai, Shen et al.: "Direct binding of alpha-actinin enhances TRPP3 channel activity." in: Journal of neurochemistry, Vol. 103, Issue 6, pp. 2391-400, 2007 (PubMed).

Geng, Okuhara, Yu et al.: "Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif." in: Journal of cell science, Vol. 119, Issue Pt 7, pp. 1383-95, 2006 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Validation Images
Did you look for something else?
back to top