phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) (C-Term), (AA 1155-1184) antibody

Details for Product No. ABIN954182
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Synonyms PLCB1, 3110043I21Rik, AI132408, Plcb, mKIAA0581, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B, PLC'1, PLCbeta1, Phosphb, RATPHOSPHB
C-Term, AA 1155-1184
(13), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(43), (25), (21), (3)
(42), (5), (1)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(29), (11), (10), (8), (4), (3), (3), (2), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954182
357.50 $
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Immunogen KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1
Isotype Ig
Specificity This antibody recognizes Human PLCB1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCB1
Background The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-1, KIAA0581, PLC beta1, PLC-I, PLC-beta-1, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1
Molecular Weight 138567 Da
Gene ID 23236
NCBI Accession NP_056007
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Woodcock, Grubb, Filtz et al.: "Selective activation of the \b\" splice variant of phospholipase Cbeta1 in chronically dilated human and mouse atria."" in: Journal of molecular and cellular cardiology, Vol. 47, Issue 5, pp. 676-83, 2009 (PubMed).

Zhang, Kwon, Vogel et al.: "PI(3,4,5)P3 potentiates phospholipase C-beta activity." in: Journal of receptor and signal transduction research, Vol. 29, Issue 1, pp. 52-62, 2009 (PubMed).

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