phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) (C-Term), (AA 1155-1184) antibody

Details for Product No. ABIN954182
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Antigen
Synonyms PLCB1, 3110043I21Rik, AI132408, Plcb, mKIAA0581, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B, PLC'1, PLCbeta1, Phosphb, RATPHOSPHB
Epitope
C-Term, AA 1155-1184
(12), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(38), (23), (21), (13), (12), (12)
Host
Rabbit
(38), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
(23), (11), (10), (6), (3), (1), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN954182
357.50 $
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Immunogen KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1
Specificity This antibody recognizes Human PLCB1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCB1
Background The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.
Alternate names: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta-1, KIAA0581, PLC beta1, PLC-I, PLC-beta-1, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1
Molecular Weight 138567 Da
Gene ID 23236
NCBI Accession NP_056007
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Zhang, Kwon, Vogel et al.: "PI(3,4,5)P3 potentiates phospholipase C-beta activity." in: Journal of receptor and signal transduction research, Vol. 29, Issue 1, pp. 52-62, 2009 (PubMed).

Woodcock, Grubb, Filtz et al.: "Selective activation of the \b\" splice variant of phospholipase Cbeta1 in chronically dilated human and mouse atria."" in: Journal of molecular and cellular cardiology, Vol. 47, Issue 5, pp. 676-83, 2009 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

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