anti-PLCD1 antibody (phospholipase C, delta 1) (N-Term)

Details for Product anti-PLCD1 Antibody No. ABIN954185
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Antigen
Synonyms NDNC3, PLC-III, AW212592, C79986, Plc1
Epitope
N-Term, AA 154-184
(20), (15), (1), (1), (1)
Reactivity
Human
(29), (6), (6), (2), (2), (2)
Host
Rabbit
(28), (1)
Clonality
Polyclonal
Conjugate
This PLCD1 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(27), (17), (3), (1), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen KLH conjugated synthetic peptide between 154-184 amino acids from the N-terminal region of human PLCD1
Isotype Ig
Specificity This antibody recognizes Human PLCD1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCD1 (PLCD1 Antibody Abstract)
Background Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]).Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-1, PLC-III, PLC-delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C delta 1, Phospholipase C-III, Phospholipase C-delta-1
Molecular Weight 85665 Da
Gene ID 5333
NCBI Accession NP_001124436
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Guo, Golebiewska, DAmico et al.: "The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24999-5008, 2010 (PubMed).

Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Segat, Brandão, Guimarães et al.: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010 (PubMed).

Godin, Ferreira, Dale et al.: "The small GTPase Ral couples the angiotensin II type 1 receptor to the activation of phospholipase C-delta 1." in: Molecular pharmacology, Vol. 77, Issue 3, pp. 388-95, 2010 (PubMed).

Validation Images
Catalog No. ABIN954185
357.50 $
Plus shipping costs $45.00
Quantity
Price
0.4 mL
357.50 $

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