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PLCD1 antibody (phospholipase C, delta 1) (N-Term)

Details for Product anti-PLCD1 Antibody No. ABIN954185, Supplier: Log in to see
Antigen
  • NDNC3
  • PLC-III
  • AW212592
  • C79986
  • Plc1
Alternatives
anti-Human PLCD1 antibody for Western Blotting
Epitope
N-Term, AA 154-184
21
15
1
1
1
Reactivity
Human
30
7
7
2
2
2
Host
Rabbit
29
1
Clonality
Polyclonal
Conjugate
This PLCD1 antibody is un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
28
20
Supplier
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Immunogen KLH conjugated synthetic peptide between 154-184 amino acids from the N-terminal region of human PLCD1
Isotype Ig
Specificity This antibody recognizes Human PLCD1 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name PLCD1 (PLCD1 Antibody Abstract)
Background Phosphoinositide-specific phospholipase C (PLC) acts as a signal transducer that generates 2 second messengers, diacylglycerol and inositol 1,4,5-trisphosphate, by hydrolyzing inositol phospholipids. PLC comprises a diverse family of enzymes that differ in structure and tissue distribution (Berridge, 1993 [PubMed 8381210]).Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase delta-1, PLC-III, PLC-delta-1, Phosphoinositide phospholipase C-delta-1, Phospholipase C delta 1, Phospholipase C-III, Phospholipase C-delta-1
Molecular Weight 85665 Da
Gene ID 5333
NCBI Accession NP_001124436
Research Area Signaling
Pathways WNT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-PLCD1 antibody (phospholipase C, delta 1) (N-Term) (ABIN954185) Western blot analysis of PLCD1 Antibody (N-term) in HL-60 cell line lysates (35ug/lan...
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Guo, Golebiewska, DAmico et al.: "The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24999-5008, 2010 (PubMed).

Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Segat, Brandão, Guimarães et al.: "Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment." in: Vaccine, Vol. 28, Issue 10, pp. 2201-6, 2010 (PubMed).

Godin, Ferreira, Dale et al.: "The small GTPase Ral couples the angiotensin II type 1 receptor to the activation of phospholipase C-delta 1." in: Molecular pharmacology, Vol. 77, Issue 3, pp. 388-95, 2010 (PubMed).