Protein O-Fucosyltransferase 2 (POFUT2) (AA 235-265), (Middle Region) antibody

Details for Product No. ABIN954233
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms C21orf80, FUT13, fc46a11, wu:fc46a11, zgc:194822, 2310011G23Rik, AI256847, BC003494
Epitope
AA 235-265, Middle Region
(7), (6), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(27), (9), (3), (1), (1), (1)
Host
Rabbit
(25), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(22), (17), (12), (3), (2)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN954233
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 235-265 amino acids from the Central region of human POFUT2
Specificity This antibody recognizes Human POFUT2 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name POFUT2
Background Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857].
Alternate names: C21orf80, FUT13, GDP-fucose protein O-fucosyltransferase 2, KIAA0958, O-FucT-2, Peptide- O-fucosyltransferase 2
Molecular Weight 49976 Da
Gene ID 23275
NCBI Accession NP_056042
Research Area Signaling, Metabolism, Organelles
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Menzel, Vellai, Takacs-Vellai et al.: "The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development." in: Genomics, Vol. 84, Issue 2, pp. 320-30, 2004 (PubMed).

Luo, Koles, Vorndam et al.: "Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9393-9, 2006 (PubMed).

Luo, Nita-Lazar, Haltiwanger: "Two distinct pathways for O-fucosylation of epidermal growth factor-like or thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9385-92, 2006 (PubMed).

Feng, Zhu: "Genome-wide searching of rare genetic variants in WTCCC data." in: Human genetics, Vol. 128, Issue 3, pp. 269-80, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top