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Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody

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Synonyms 1110030G05Rik, AU041779, Gcap3, ACID2, PTOV-1
AA 28-56, N-Term
(19), (15), (2), (1), (1), (1)
Human, Mouse (Murine)
(37), (19), (17), (2)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(26), (16), (14), (11), (5), (1), (1)
Pubmed 5 references available
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Quantity 0.4 mL
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide - KLH conjugated corresponding to the N-terminal region between 28-56 amino acids of Human PTOV1. Genename: PTOV1.
Isotype Ig
Specificity This antibody recognizes Human and Mouse PTOC1 at N-term.
Purification Protein A column, followed by peptide affinity purification
Alternative Name PTOV1 (PTOV1 Antibody Abstract)
Background PTOV1 may activate transcription. It is Required for nuclear translocation of FLOT1 and promotes cell proliferation.Synonyms: ACID2, Activator interaction domain-containing protein 2, PTOV-1, Prostate tumor-overexpressed gene 1 protein
Molecular Weight 46869 Da
Gene ID 53635
NCBI Accession NP_059128
Research Area Cancer, Cell Cycle, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody (ABIN954371) Immunohistochemistry analysis in human brain tissue (Formalin-fixed, Paraffin-embedde...
Western Blotting (WB) image for anti-Prostate Tumor Overexpressed 1 (PTOV1) (AA 28-56), (N-Term) antibody (ABIN954371) western blot analysis in mouse cerebellum tissue lysates (35ug/lane) using PTOV1  Ant...
Background publications Morote, Fernández, Alaña et al.: "PTOV1 expression predicts prostate cancer in men with isolated high-grade prostatic intraepithelial neoplasia in needle biopsy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 9, pp. 2617-22, 2008 (PubMed).

Santamaría, Castellanos, Gómez et al.: "PTOV1 enables the nuclear translocation and mitogenic activity of flotillin-1, a major protein of lipid rafts." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1900-11, 2005 (PubMed).

Mittler, Stühler, Santolin et al.: "A novel docking site on Mediator is critical for activation by VP16 in mammalian cells." in: The EMBO journal, Vol. 22, Issue 24, pp. 6494-504, 2003 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Santamaría, Fernández, Farré et al.: "PTOV-1, a novel protein overexpressed in prostate cancer, shuttles between the cytoplasm and the nucleus and promotes entry into the S phase of the cell division cycle." in: The American journal of pathology, Vol. 162, Issue 3, pp. 897-905, 2003 (PubMed).

Catalog No. ABIN954371
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