Pseudouridylate Synthase 1 (PUS1) (C-Term), (AA 329-358) antibody

Details for Product No. ABIN954388
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Antigen
Synonyms PUS1, A730013B20Rik, MPUS1, mPus1p, MLASA1
Epitope
C-Term, AA 329-358
(8), (7), (5), (5), (2), (1)
Reactivity
Human
(22), (8), (3)
Host
Rabbit
(23), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(25), (9), (6), (5), (4), (4), (3)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN954388
357.50 $
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Immunogen KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of Human PUS1
Specificity This antibody recognizes Humann PUS1 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name PUS1
Background This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants
Alternate names: MGC11268, MLASA1, PP8985, Pseudouridylate synthase 1, tRNA pseudouridine synthase A mitochondrial, tRNA pseudouridine(38-40) synthase tRNA pseudouridylate synthase I, tRNA-uridine isomerase I
Molecular Weight 47470 Da
Gene ID 80324
NCBI Accession NP_001002019
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Demling: "Burns: what are the pharmacological treatment options?" in: Expert opinion on pharmacotherapy, Vol. 9, Issue 11, pp. 1895-908, 2008 (PubMed).

Bergmann, Campagna, McLoughlin et al.: "Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations." in: Pediatric blood & cancer, Vol. 54, Issue 2, pp. 273-8, 2009 (PubMed).

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