RAN Binding Protein 3 (RANBP3) (N-Term) antibody

Details for Product No. ABIN954449
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Antigen
Synonyms ranbp3, MGC79798, 2610024N24Rik, AA408221
Epitope
N-Term
(10), (7), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(36), (15), (13), (13), (12), (12)
Host
Rabbit
(33), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(24), (11), (10), (7), (7), (4), (2), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN954449
357.50 $
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Isotype Ig
Specificity This antibody recognizes Human RANBP3 (N-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name RANBP3
Background RANBP3 is a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: Ran-binding protein 3
Molecular Weight 60210 Da
Gene ID 8498
NCBI Accession NP_015559
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Nemergut, Lindsay, Brownawell et al.: "Ran-binding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17385-8, 2002 (PubMed).

Hakata, Yamada, Shida: "A multifunctional domain in human CRM1 (exportin 1) mediates RanBP3 binding and multimerization of human T-cell leukemia virus type 1 Rex protein." in: Molecular and cellular biology, Vol. 23, Issue 23, pp. 8751-61, 2003 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Yoon, Shin, Liu et al.: "Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport." in: Molecular cell, Vol. 29, Issue 3, pp. 362-75, 2008 (PubMed).

Dai, Lin, Chang et al.: "Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-beta signaling." in: Developmental cell, Vol. 16, Issue 3, pp. 345-57, 2009 (PubMed).

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