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Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 (RCBTB1) (AA 349-377), (Middle Region) antibody

Details for Product No. ABIN954490
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Antigen
Synonyms fj43a07, zgc:56037, wu:fj43a07, MGC81035, rcbtb1, CLLD7, CLLL7, GLP, RP11-185C18.1, 5430409I18Rik, AW111883
Epitope
AA 349-377, Middle Region
(8), (7), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(51), (37), (26), (23), (23), (23), (11)
Host
Rabbit
(49), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(34), (19), (16), (10), (7), (2), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN954490
357.50 $
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Immunogen KLH conjugated synthetic peptide between 349-377 amino acids from the Central region of Human RCBTB1. Genename: RCBTB1
Specificity This antibody recognizes Human RCBTB1 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name RCBTB1
Background This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
Alternate names: CLL deletion region gene 7 protein, CLLD7, Chronic lymphocytic leukemia deletion region gene 7 protein, RCC1 and BTB domain-containing protein 1, Regulator of chromosome condensation and BTB domain-containing protein 1
Molecular Weight 58252 Da
Gene ID 55213
NCBI Accession NP_060661
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Guo, Tardif, Ghelima et al.: "A novel angiotensin II type 1 receptor-associated protein induces cellular hypertrophy in rat vascular smooth muscle and renal proximal tubular cells." in: The Journal of biological chemistry, Vol. 279, Issue 20, pp. 21109-20, 2004 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Genuneit, Cantelmo, Weinmayr et al.: "A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 12, pp. 1875-88, 2010 (PubMed).

Validation Images
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