Ras Homolog Enriched in Brain Like 1 (RHEBL1) (N-Term), (AA 24-53) antibody

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Synonyms RHEBL1c, 1810036J22Rik, rhebl1c, MGC75978, RHEBL1
N-Term, AA 24-53
(2), (2), (1), (1), (1), (1)
Human, Mouse (Murine)
(11), (3), (1), (1), (1)
(10), (3)
ELISA, Western Blotting (WB)
(11), (3), (2)
Pubmed 4 references available
Catalog no. ABIN954538
Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of Human RHEBL1. Genename: RHEBL1
Specificity This antibody recognizes Mouse RHEBL1 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name RHEBL1
Background RHEBL1 binds GTP and exhibits intrinsic GTPase activity. May activate NF-kappa-B- mediated gene transcription. Promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Alternate names: GTPase RhebL1, Ras homolog enriched in brain like-1 c, Rheb-like protein 1, Rheb2, RhebL1c
Molecular Weight 20682 Da
Gene ID 121268
NCBI Accession NP_653194
Research Area Signaling, DNA/RNA
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Tabancay, Gau, Machado et al.: "Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K." in: The Journal of biological chemistry, Vol. 278, Issue 41, pp. 39921-30, 2003 (PubMed).

Barrios-Rodiles, Brown, Ozdamar et al.: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Tee, Blenis, Proud: "Analysis of mTOR signaling by the small G-proteins, Rheb and RhebL1." in: FEBS letters, Vol. 579, Issue 21, pp. 4763-8, 2005 (PubMed).

Yuan, Shan, Chen et al.: "Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B." in: Molecular biology reports, Vol. 32, Issue 4, pp. 205-14, 2005 (PubMed).

Hosts (10), (3)
Reactivities (11), (3), (1), (1), (1)
Applications (11), (3), (2)
Epitopes (2), (2), (1), (1), (1), (1)
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