Ribosomal Protein, Large, P0 (RPLP0) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN954604
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Antigen
Synonyms
AP3, Ap3, Ape, CG7490, Dmel\\CG7490, LP0, P0, P35, PO, RLA0, RPL P0, RpP0, RpPO, Rplp0, l(3)0154, l(3)01544, p0, RPLP0, arp, fa56b12, fb04a12, wu:fa56b12, wu:fb15a08, wu:fk48c12, arbp, l10e, lp0, prlp ... show more
AP3, Ap3, Ape, CG7490, Dmel\\CG7490, LP0, P0, P35, PO, RLA0, RPL P0, RpP0, RpPO, Rplp0, l(3)0154, l(3)01544, p0, RPLP0, arp, fa56b12, fb04a12, wu:fa56b12, wu:fb15a08, wu:fk48c12, arbp, l10e, lp0, prlp0, rpp0, L10E, PRLP0, RPP0, 36B4, Arbp, ARBP show less
Epitope
N-Term, AA 1-30
(8), (7), (2), (1), (1), (1), (1)
Reactivity
Human
(32), (18), (18), (14), (14), (13), (13), (2), (2)
Host
Rabbit
(31), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(25), (11), (10), (4), (3), (3), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN954604
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Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Human RPLP0 Genename: RPLP0
Specificity Recognizes RPLP0 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RPLP0
Background RPLP0 was catalyze systhesis by ribosomes, consisting of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This peotein encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. This protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm.
Alternate names: 60S acidic ribosomal protein P0, 60S ribosomal protein L10E
Gene ID 6175
NCBI Accession NP_000993
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).

Chang, Chen, Chen et al.: "Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells." in: Oncogene, Vol. 27, Issue 3, pp. 332-8, 2008 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Rinne, Clements, Lamme et al.: "A novel translation re-initiation mechanism for the p63 gene revealed by amino-terminal truncating mutations in Rapp-Hodgkin/Hay-Wells-like syndromes." in: Human molecular genetics, Vol. 17, Issue 13, pp. 1968-77, 2008 (PubMed).

Vascotto, Fantini, Romanello et al.: "APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process." in: Molecular and cellular biology, Vol. 29, Issue 7, pp. 1834-54, 2009 (PubMed).

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