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Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody

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Synonyms MGC81290, RPS6KC1, AA682037, B130003F20Rik, C80612, Rpk118, RPK118, humS6PKh1
AA 19-47, N-Term
(17), (15), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(25), (20), (2)
(33), (4)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(34), (26), (17), (9), (4), (1), (1)
Pubmed 4 references available
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Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 19-47 amino acids from the N-terminal region of Human RPS6KC1. Genename: RPS6KC1
Isotype Ig
Specificity Recognizes RPS6KC1 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name RPS6KC1 / RPK118 (RPS6KC1 Antibody Abstract)
Background RPS6KC1 shows homology to the S6 kinase family of serine/threonine kinases. It is a sphingosine kinase-1 (SPHK1)-binding protein that may be involved in transmitting sphingosine 1 phosphate (SPP)-mediated signaling into the cell. Cellular localization: Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.Synonyms: 52 kDa ribosomal protein S6 kinase, Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein, Ribosomal protein S6 kinase delta-1, S6K-delta-1, SPHK1-binding protein
Gene ID 26750
NCBI Accession NP_001129610
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody (ABIN954626) Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human skeletal mus...
Western Blotting (WB) image for anti-Ribosomal Protein S6 Kinase, 52kDa, Polypeptide 1 (RPS6KC1) (AA 19-47), (N-Term) antibody (ABIN954626) Western blot analysis in Mouse liver tissue lysates (35ug/lane) using RPS6KC1 Antibod...
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Liu, Yang, Yuan et al.: "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains." in: Molecules and cells, Vol. 19, Issue 1, pp. 39-45, 2005 (PubMed).

Lehner, Semple, Brown et al.: "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region." in: Genomics, Vol. 83, Issue 1, pp. 153-67, 2003 (PubMed).

Hayashi, Okada, Igarashi et al.: "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein." in: The Journal of biological chemistry, Vol. 277, Issue 36, pp. 33319-24, 2002 (PubMed).

Catalog No. ABIN954626
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