Retinoid X Receptor beta antibody (Middle Region)

Catalog No. ABIN954648

Product Details anti-Retinoid X Receptor beta Antibody

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Binding Specificity: AA 262-292, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: Recognizes RXRB (Center).

Purification: Protein A column followed by peptide Affinity purification

Immunogen: KLH conjugated synthetic peptide between 262~292 amino acids from the Central region of Human RXRB Genename: RXRB

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: RXR-beta / RXRB (RXRB Products)

Background: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.Synonyms: H-2RIIBP, NR2B2, Nuclear Receptor Coregulator 1, Nuclear receptor subfamily 2 group B member 2, Rcor-1, Retinoic acid receptor RXR-beta, Retinoid X receptor beta

Gene ID: 6257

NCBI Accession: NP_068811

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway