You are viewing an incomplete version of our website. Please click to reload the website as full version.

Aralkylamine N-Acetyltransferase (AANAT) (AA 33-63), (N-Term) antibody

Details for Product No. ABIN954733, Supplier: Log in to see
Antigen
  • DSPS
  • SNAT
  • AA-NAT
  • Nat4
  • Nat-2
  • Snat
Epitope
N-Term, AA 33-63
15
14
13
2
2
1
1
1
1
Reactivity
Human
39
22
19
Host
Rabbit
42
Clonality
Polyclonal
Conjugate
Un-conjugated
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
27
16
13
4
4
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 33~63 amino acids from the N-terminal region of human AANAT
Isotype Ig
Specificity This antibody reacts to Serotonin acetylase.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name Serotonin Acetylase (AANAT Antibody Abstract)
Background AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.Synonyms: AA-NAT, AANAT, Aralkylamine N-acetyltransferase, SNAT, Serotonin N-acetyltransferase
Gene ID 15
NCBI Accession NP_001079
Research Area Enzymes
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Aralkylamine N-Acetyltransferase (AANAT) (AA 33-63), (N-Term) antibody (ABIN954733) Western blot analysis of AANAT Antibody (N-term) in Y79 cell line lysates (35 µg/lane...
Background publications Mansour, Talkowski, Wood et al.: "Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia." in: Bipolar disorders, Vol. 11, Issue 7, pp. 701-10, 2009 (PubMed).

Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).