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Taste Receptor, Type 1, Member 2 (TAS1R2) (AA 698-726), (C-Term) antibody

Details for Product No. ABIN955081, Supplier: Login to see
Antigen
  • GPR71
  • T1R2
  • TR2
  • Aldh4a1
  • Gpr71
  • Tr2
  • T1r2
Epitope
C-Term, AA 698-726
22
15
15
4
3
2
1
1
1
Reactivity
Human
57
17
16
1
Host
Rabbit
48
16
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
45
31
11
7
5
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 698-726 amino acids from the C-terminal region of human TAS1R2
Isotype Ig
Specificity This antibody reacts to TAS1R2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name TAS1R2 / GPR71 (TAS1R2 Antibody Abstract)
Background Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.Synonyms: G-protein coupled receptor 71, Sweet taste receptor T1R2, TR2, Taste receptor type 1 member 2
Molecular Weight 95183 Da
Gene ID 80834
NCBI Accession NP_689418
Research Area Signaling, Receptors
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Taste Receptor, Type 1, Member 2 (TAS1R2) (AA 698-726), (C-Term) antibody (ABIN955081) TAS1R2 Antibody (C-term) western blot analysis in K562 cell line lysates (35µg/lane)....
Background publications Wendell, Wang, Brown et al.: "Taste genes associated with dental caries." in: Journal of dental research, Vol. 89, Issue 11, pp. 1198-202, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Assadi-Porter, Maillet, Radek et al.: "Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor." in: Journal of molecular biology, Vol. 398, Issue 4, pp. 584-99, 2010 (PubMed).

Chandrashekar, Hoon, Ryba et al.: "The receptors and cells for mammalian taste." in: Nature, Vol. 444, Issue 7117, pp. 288-94, 2006 (PubMed).

Galindo-Cuspinera, Winnig, Bufe et al.: "A TAS1R receptor-based explanation of sweet 'water-taste'." in: Nature, Vol. 441, Issue 7091, pp. 354-7, 2006 (PubMed).