Taste Receptor, Type 2, Member 44 (TAS2R31) (C-Term), (AA 279-309) antibody

Details for Product No. ABIN955084
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Synonyms TAS2R44, T2R31, T2R44, T2R53
C-Term, AA 279-309
(15), (14), (2)
(18), (1)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(19), (10), (3), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN955084
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Immunogen KLH conjugated synthetic peptide between 279-309 amino acids from the C-terminal region of human TAS2R31
Isotype Ig
Specificity This antibody reacts to TAS2R31.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name TAS2R44
Background TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.Synonyms: T2R53, Taste receptor T2R44, Taste receptor type 2 member 44
Molecular Weight 35296 Da
Gene ID 259290
NCBI Accession NP_795366
Research Area Neurology
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Pronin, Xu, Tang et al.: "Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin." in: Current biology : CB, Vol. 17, Issue 16, pp. 1403-8, 2007 (PubMed).

Kuhn, Bufe, Winnig et al.: "Bitter taste receptors for saccharin and acesulfame K." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 24, Issue 45, pp. 10260-5, 2004 (PubMed).

Fischer, Gilad, Man et al.: "Evolution of bitter taste receptors in humans and apes." in: Molecular biology and evolution, Vol. 22, Issue 3, pp. 432-6, 2005 (PubMed).

Pronin, Tang, Connor et al.: "Identification of ligands for two human bitter T2R receptors." in: Chemical senses, Vol. 29, Issue 7, pp. 583-93, 2004 (PubMed).

Zhang, Hoon, Chandrashekar et al.: "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways." in: Cell, Vol. 112, Issue 3, pp. 293-301, 2003 (PubMed).

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