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Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody

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Synonyms TSEPA, C6orf190, C6orf207, GASP, SPOT, bA325O24.3, bA325O24.4, A430108D01, BB160712, E430004N04Rik, Gasp, Tsepa, thylex, C9H6ORF190, im:7138580, tsepa
AA 566-595, C-Term
(28), (15), (5), (1), (1)
Human, Mouse (Murine)
(43), (30), (13)
(38), (13), (4), (3), (1)
(6), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(45), (26), (14), (11), (5), (5), (3), (3), (2), (2), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS
Isotype Ig
Specificity This antibody detects THEMIS (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name THEMIS (THEMIS Antibody Abstract)
Background This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.Synonyms: C6orf190, C6orf207, Protein
Gene ID 387357
NCBI Accession NP_001010923
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody (ABIN955183) THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin...
Western Blotting (WB) image for anti-Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody (ABIN955183) THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35 µg/l...
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Bhatti, Doody, Rajaraman et al.: "Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists." in: Radiation research, Vol. 173, Issue 2, pp. 214-24, 2010 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Patrick, Oda, Hayakawa et al.: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, 2009 (PubMed).

Catalog No. ABIN955183
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