You are viewing an incomplete version of our website. Please click to reload the website as full version.

Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody

Details for Product No. ABIN955183, Supplier: Login to see
Antigen
  • TSEPA
  • C6orf190
  • C6orf207
  • GASP
  • SPOT
  • bA325O24.3
  • bA325O24.4
  • A430108D01
  • BB160712
  • E430004N04Rik
  • Gasp
  • Tsepa
  • thylex
  • C9H6ORF190
  • im:7138580
  • tsepa
Epitope
AA 566-595, C-Term
28
15
5
1
1
Reactivity
Human, Mouse (Murine)
43
30
13
Host
Rabbit
38
13
4
3
1
Clonality
Polyclonal
Conjugate
Un-conjugated
6
4
4
4
3
3
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
45
26
14
11
5
5
3
3
2
2
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 566-595 amino acids from the C-terminal region of human THEMIS
Isotype Ig
Specificity This antibody detects THEMIS (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name THEMIS (THEMIS Antibody Abstract)
Background This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.Synonyms: C6orf190, C6orf207, Protein
Gene ID 387357
NCBI Accession NP_001010923
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody (ABIN955183) THEMIS Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin...
Western Blotting (WB) image for anti-Thymocyte Selection Associated (THEMIS) (AA 566-595), (C-Term) antibody (ABIN955183) THEMIS Antibody (C-term) western blot analysis in mouse liver tissue lysates (35 µg/l...
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Bhatti, Doody, Rajaraman et al.: "Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists." in: Radiation research, Vol. 173, Issue 2, pp. 214-24, 2010 (PubMed).

Talmud, Drenos, Shah et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).

Patrick, Oda, Hayakawa et al.: "Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 38, pp. 16345-50, 2009 (PubMed).