Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1) (AA 297-326), (C-Term) antibody

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Synonyms GNAT1, gbt1, gnatr, csnbad3, CSNBAD3, GBT1, GNATR, wu:fk56e06, Gnat-1, Ird1, Ird2, Tralpha, irdc, irdr, transducin
AA 297-326, C-Term
(15), (14), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
(39), (13), (11), (2), (2), (2), (1), (1)
(2), (2), (2), (2), (2), (2)
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(41), (25), (16), (14), (3), (3)
Pubmed 4 references available
Quantity 0.4 mL
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Immunogen conjugated synthetic peptide between 297~326 amino acids from the C-terminal region of Human Transducin alpha-1 chain / GNAT1
Isotype Ig
Specificity This antibody recognizes Human Transducin alpha-1 chain / GNAT1 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name Transducin alpha-1 Chain / GNAT1 (GNAT1 Antibody Abstract)
Background Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells.Synonyms: GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1
Molecular Weight 40041 Da
Gene ID 2779
NCBI Accession NP_000163
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Luttrell: "Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors." in: Molecular biotechnology, Vol. 39, Issue 3, pp. 239-64, 2008 (PubMed).

Szabo, Kreienkamp, Rosenberg et al.: "p.Gln200Glu, a putative constitutively active mutant of rod alpha-transducin (GNAT1) in autosomal dominant congenital stationary night blindness." in: Human mutation, Vol. 28, Issue 7, pp. 741-2, 2007 (PubMed).

Yi, Ren, Peng et al.: "[Expression, loss of heterozygosity, and methylation of GNAT1 gene in nasopharyngeal carcinoma]." in: Ai zheng = Aizheng = Chinese journal of cancer, Vol. 26, Issue 1, pp. 9-14, 2007 (PubMed).

Muzny, Scherer, Kaul et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).

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Catalog No. ABIN955309
$ 357.50
Plus shipping costs $45.00
0.4 mL
$ 357.50

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