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Tropomodulin 1 antibody (TMOD1) (AA 169-198)

Details for Product anti-TMOD1 Antibody No. ABIN955335, Supplier: Login to see New
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Synonyms tropomodulin-1, TMOD1, si:ch211-288h2.6, D9S57E, ETMOD, TMOD, E-Tmod, Tmod
AA 169-198, Middle Region
(15), (13), (11), (6), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
(61), (7), (7), (4), (1), (1), (1), (1), (1), (1)
(33), (26), (6)
This Tropomodulin 1 antibody is un-conjugated
(3), (3), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(57), (30), (19), (13), (3), (3), (2), (2), (2)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human TMOD1
Isotype Ig
Specificity This antibody detects Tropomodulin-1 (TMOD1) (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name Tropomodulin-1 (TMOD1) (TMOD1 Antibody Abstract)
Background TMOD1 is a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene.Synonyms: D9S57E, E-Tmod, Erythrocyte tropomodulin, TMOD
Gene ID 7111
NCBI Accession NP_001159588
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Tropomodulin 1 antibody (TMOD1) (AA 169-198) (ABIN955335) TMOD1 Antibody (Center) western blot analysis in A549 cell line lysates (35 µg/lane)....
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Kong, Kedes: "Leucine 135 of tropomodulin-1 regulates its association with tropomyosin, its cellular localization, and the integrity of sarcomeres." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9589-99, 2006 (PubMed).

Vera, Lao, Hamelberg et al.: "Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction." in: Archives of biochemistry and biophysics, Vol. 444, Issue 2, pp. 130-8, 2005 (PubMed).

Pawlak, McGarvey, Nguyen et al.: "Alterations in tropomyosin isoform expression in human transitional cell carcinoma of the urinary bladder." in: International journal of cancer. Journal international du cancer, Vol. 110, Issue 3, pp. 368-73, 2004 (PubMed).

Rho, Chun, Lee et al.: "The interaction between E-tropomodulin and thymosin beta-10 rescues tumor cells from thymosin beta-10 mediated apoptosis by restoring actin architecture." in: FEBS letters, Vol. 557, Issue 1-3, pp. 57-63, 2004 (PubMed).

Catalog No. ABIN955335
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