Unc-51 Like Kinase 1 (C. Elegans) (ULK1) antibody

Details for Product No. ABIN955448
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Antigen
Synonyms Unc51.1, AU041434, mKIAA0722, ATG1, ATG1A, UNC51, hATG1, ULK1, si:dkey-11o18.7, ulk1
Reactivity
Human, Mouse (Murine)
(61), (31), (28), (24), (12), (12), (2), (1)
Host
Rabbit
(58), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS)
(30), (20), (13), (12), (12), (7), (4), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN955448
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide selected from Human Unc-51-like kinase 1 (ULK1) Genename: ULK1
Specificity This antibody recognizes Human and Mouse Unc-51-like kinase 1 (ULK1).
Purification Affinity Chromatography on Proteinn A
Alternative Name Unc-51-like kinase 1 (ULK1)
Background ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).
Alternate names: KIAA0722, Serine/threonine-protein kinase ULK1
Molecular Weight 112601 Da
Gene ID 8408
NCBI Accession NP_003556
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Greenman, Stephens, Smith et al.: "Patterns of somatic mutation in human cancer genomes...." in: Nature, Vol. 446, Issue 7132, pp. 153-8, 2007 (PubMed).

Hosts (58), (4), (1)
Reactivities (61), (31), (28), (24), (12), (12), (2), (1)
Applications (30), (20), (13), (12), (12), (7), (4), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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