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Unc-51 Like Kinase 1 (C. Elegans) (ULK1) antibody

Details for Product No. ABIN955448, Supplier: Login to see
Antigen
  • ULK1
  • si:dkey-11o18.7
  • ulk1
  • ATG1
  • ATG1A
  • UNC51
  • Unc51.1
  • hATG1
  • AU041434
  • mKIAA0722
Reactivity
Human, Mouse (Murine)
226
36
33
6
3
2
1
1
1
1
1
1
Host
Rabbit
217
6
3
Clonality
Polyclonal
Conjugate
Un-conjugated
21
20
20
18
18
18
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
138
121
75
22
15
14
10
4
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide selected from Human Unc-51-like kinase 1 (ULK1) Genename: ULK1
Isotype Ig
Specificity This antibody recognizes Human and Mouse Unc-51-like kinase 1 (ULK1).
Purification Affinity Chromatography on Proteinn A
Alternative Name Unc-51-Like Kinase 1 (ULK1) (ULK1 Antibody Abstract)
Background ULK1 is involved in autophagy. It is required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. It is involved in axon growth (By similarity) and plays an essential role in neurite extension of cerebellar granule cells (By similarity).Synonyms: KIAA0722, Serine/threonine-protein kinase ULK1
Molecular Weight 112601 Da
Gene ID 8408
NCBI Accession NP_003556
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Unc-51 Like Kinase 1 (C. Elegans) (ULK1) antibody (ABIN955448) Flow cytometric analysis of k562 cells using Denatured ATG1 Antibody  (bottom histogr...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Unc-51 Like Kinase 1 (C. Elegans) (ULK1) antibody (ABIN955448) Formalin-fixed and paraffin-embedded human skeletal muscle reacted with Denatured ATG...
Western Blotting (WB) image for anti-Unc-51 Like Kinase 1 (C. Elegans) (ULK1) antibody (ABIN955448) Western blot analysis of Denatured ATG1 Antibody  in mouse cerebellum tissue lysates ...
Background publications Greenman, Stephens, Smith et al.: "Patterns of somatic mutation in human cancer genomes. ..." in: Nature, Vol. 446, Issue 7132, pp. 153-8, 2007 (PubMed).