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Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) antibody

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Synonyms hapln3, USP12P1, usp12, Ubh1, ubh1, usp12l1, UBH1, USP12L1, USP12, sb:eu882, wu:fi09d12
AA 221-251, Middle Region
(21), (15), (15), (14), (9), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(56), (26), (6), (1), (1), (1), (1), (1)
(65), (7)
(6), (6), (6), (6), (6), (6)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(65), (49), (16), (3), (2)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 221-251 amino acids from the Central region of human USP12
Isotype Ig
Specificity This antibody detects USP12 (Center).
Cross-Reactivity (Details) Species reactivity (expected):Bovine, Xenopus.
Species reactivity (tested):Human, Mouse.
Purification Protein A column followed by peptide affinity purification
Alternative Name USP12 (USP12 Antibody Abstract)
Background USP12is a deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.Synonyms: Deubiquitinating enzyme 12, UBH1, USP12L1, Ubiquitin carboxyl-terminal hydrolase 12, Ubiquitin thioesterase 12, Ubiquitin-hydrolyzing enzyme 1, Ubiquitin-specific-processing protease 12
Gene ID 219333
NCBI Accession NP_872294
Research Area Proteolysis / Ubiquitin
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) antibody (ABIN955485) USP12 Antibody (Center) western blot analysis in A375 cell line lysates (35 µg/lane)....
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 12 (USP12) (AA 221-251), (Middle Region) antibody (ABIN955485) USP12 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35 µg/...
Background publications Kee, Yang, Cohn et al.: "WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex." in: The Journal of biological chemistry, Vol. 285, Issue 15, pp. 11252-7, 2010 (PubMed).

Asano, Matsushita, Umeno et al.: "A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population." in: Nature genetics, Vol. 41, Issue 12, pp. 1325-9, 2009 (PubMed).

Cohn, Kee, Haas et al.: "UAF1 is a subunit of multiple deubiquitinating enzyme complexes." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 5343-51, 2009 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Catalog No. ABIN955485
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