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Arginine Vasopressin Receptor 1A (AVPR1A) (AA 354-383), (C-Term) antibody

Details for Product No. ABIN955500, Supplier: Log in to see
Antigen
  • AVPR V1a
  • AVPR1
  • V1aR
  • AVPR
  • Avpr1
  • V1a
  • VT4
Epitope
C-Term, AA 354-383
28
15
4
4
3
3
3
2
2
2
1
1
1
Reactivity
Human
53
29
10
3
2
2
1
1
1
Host
Rabbit
53
14
10
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
7
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
64
49
4
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 354-383 amino acids from the C-terminal region of human AVPR1A
Isotype Ig
Specificity This antibody reacts to Vasopressin V1a receptor.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name Vasopressin V1a Receptor (AVPR1A Antibody Abstract)
Background The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis. [provided by RefSeq].Synonyms: AVPR V1, AVPR1, AVPR1A, Antidiuretic hormone receptor 1a, Vascular/hepatic-type arginine vasopressin receptor
Gene ID 552
NCBI Accession NP_000697
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Arginine Vasopressin Receptor 1A (AVPR1A) (AA 354-383), (C-Term) antibody (ABIN955500) AVPR1A Antibody (C-term) western blot analysis in A375 cell line lysates (35µg/lane)....
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Yang, Cho, Yoo et al.: "Association study between single nucleotide polymorphisms in promoter region of AVPR1A and Korean autism spectrum disorders." in: Neuroscience letters, Vol. 479, Issue 3, pp. 197-200, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).