WFDC1 antibody (C-Term, His163)

Catalog No. ABIN955571

Product Details anti-WFDC1 Antibody

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Binding Specificity: AA 147-177, C-Term, His163

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects PS20 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 147-177 (H163)amino acids from the C-terminal region of human WFDC1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for WFDC1

Target: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Alternative Name: WFDC1 / PS20 (WFDC1 Products)

Synonyms: WFDC1 antibody, zgc:158671 antibody, PS20 antibody, 2310058A03Rik antibody, ps20 antibody, WAP four-disulfide core domain 1 antibody, WFDC1 antibody, wfdc1 antibody, Wfdc1 antibody

Background: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.Synonyms: Prostate stromal protein ps20, WAP four-disulfide core domain protein 1, ps20 growth inhibitor

Gene ID: 58189

NCBI Accession: NP_067020