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Zinc Finger, FYVE Domain Containing 1 (ZFYVE1) (AA 144-173), (N-Term) antibody

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Synonyms DFCP1, SR3, TAFF1, ZNFN2A1, G630053K23, mKIAA1589
N-Term, AA 144-173
(19), (15), (3), (2), (2), (1), (1), (1), (1), (1), (1)
(33), (6), (6), (4), (4), (4), (4)
(29), (4)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(31), (16), (2), (2)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human ZFYVE1
Isotype Ig
Specificity This antibody detects ZFYVE1 (N-term).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name ZFYVE1 (ZFYVE1 Antibody Abstract)
Background The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.Synonyms: DFCP1, Double FYVE-containing protein 1, KIAA1589, PP10436, SR3, TAFF1, Tandem FYVE fingers-1, ZNFN2A1, Zinc finger FYVE domain-containing protein 1
Gene ID 53349
NCBI Accession NP_067083
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Zinc Finger, FYVE Domain Containing 1 (ZFYVE1) (AA 144-173), (N-Term) antibody (ABIN955666) ZFYVE1 Antibody (N-term) western blot analysis in human placenta tissue lysates (35 µ...
Background publications Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).

Heilig, Eckenberg, Petit et al.: "The DNA sequence and analysis of human chromosome 14. ..." in: Nature, Vol. 421, Issue 6923, pp. 601-7, 2003 (PubMed).

Krugmann, Anderson, Ridley et al.: "Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices. ..." in: Molecular cell, Vol. 9, Issue 1, pp. 95-108, 2002 (PubMed).

Cheung, Trinkle-Mulcahy, Cohen et al.: "Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi." in: The Biochemical journal, Vol. 355, Issue Pt 1, pp. 113-21, 2001 (PubMed).

Dwyer: "Cell surface saccharides of Trypanosoma lewis i. II. Lectin-mediated agglutination and fine-structure cytochemical detection of lectin-binding sites." in: Journal of cell science, Vol. 22, Issue 1, pp. 1-19, 1976 (PubMed).

Catalog No. ABIN955666
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