Zinc Finger, FYVE Domain Containing 1 (ZFYVE1) (N-Term), (AA 144-173) antibody

Details for Product No. ABIN955666
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Antigen
Synonyms DFCP1, SR3, TAFF1, ZNFN2A1, G630053K23, mKIAA1589
Epitope
N-Term, AA 144-173
(8), (7), (2), (1), (1), (1), (1)
Reactivity
Human
(17), (2), (2), (2), (2), (2), (2)
Host
Rabbit
(15), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(17), (7), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN955666
357.50 $
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Immunogen KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human ZFYVE1
Specificity This antibody detects ZFYVE1 (N-term).
Purification Protein A column followed by peptide affinity purification
Alternative Name ZFYVE1
Background The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.
Alternate names: DFCP1, Double FYVE-containing protein 1, KIAA1589, PP10436, SR3, TAFF1, Tandem FYVE fingers-1, ZNFN2A1, Zinc finger FYVE domain-containing protein 1
Gene ID 53349
NCBI Accession NP_067083
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Dwyer: "Cell surface saccharides of Trypanosoma lewis i. II. Lectin-mediated agglutination and fine-structure cytochemical detection of lectin-binding sites." in: Journal of cell science, Vol. 22, Issue 1, pp. 1-19, 1976 (PubMed).

Cheung, Trinkle-Mulcahy, Cohen et al.: "Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi." in: The Biochemical journal, Vol. 355, Issue Pt 1, pp. 113-21, 2001 (PubMed).

Krugmann, Anderson, Ridley et al.: "Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices." in: Molecular cell, Vol. 9, Issue 1, pp. 95-108, 2002 (PubMed).

Heilig, Eckenberg, Petit et al.: "The DNA sequence and analysis of human chromosome 14." in: Nature, Vol. 421, Issue 6923, pp. 601-7, 2003 (PubMed).

Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).

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