Alkaline Phosphatase, Placental (ALP) antibody

Details for Product No. ABIN965542
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Antigen
Synonyms Akp2, alp, zgc:56672, ALP, DDBDRAFT_0205491, DDBDRAFT_0231570, DDB_0205491, DDB_0231570, ECK0378, JW0374, psiA, PALP, PLAP, PLAP-1, ALPI, ALP1, CRASH, 2410004D18Rik, AU040643, AW060375, Actn2lp, Alp
Reactivity
Human
(132), (11), (11), (1), (1), (1)
Host
Mouse
(72), (60), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(5), (3), (3), (3), (3), (3)
Application
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
(76), (60), (53), (32), (25), (9), (8), (7), (4), (4), (1), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN965542
426.25 $
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Immunogen Purified recombinant fragment of human ALPP expressed in E. Coli.
Clone 3E5
Isotype IgG2b
Purification Ascitic fluid
Alternative Name ALPP
Background There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placentallike form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Synonyms: ALP, PALP, PLAP, FLJ61142, ALPP
Molecular Weight 58kDa
Gene ID 250
Application Notes Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Chen, Anderson, Hiroi et al.: "Proprotein interaction with the GPI transamidase." in: Journal of cellular biochemistry, Vol. 88, Issue 5, pp. 1025-37, 2003 (PubMed).

Llinas, Stura, Ménez et al.: "Structural studies of human placental alkaline phosphatase in complex with functional ligands." in: Journal of molecular biology, Vol. 350, Issue 3, pp. 441-51, 2005 (PubMed).

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