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Details for Product No. ABIN965991

Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

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Antigen
Synonyms
F-LAN-1, F-LANa, FLANa, BC005682, CGI-101, Derlin-2, F-lana, Flana, RP23-83I13.8, zgc:110436, DERLIN-2.2, T4B21.2, T4B21_2, DERLIN-2.1, T8O5.20, T8O5_20, DDBDRAFT_0186360, DDBDRAFT_0266773, DDB_018636 ... show more
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN965991
Quantity 0.1 mg
Price
316.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name DERL2
Background DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.
Research Area Signaling
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Lai, Chou, Chang et al.: "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." in: Genome research, Vol. 10, Issue 5, pp. 703-13, 2000 (PubMed).

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, 2001 (PubMed).

Lilley, Ploegh: "A membrane protein required for dislocation of misfolded proteins from the ER." in: Nature, Vol. 429, Issue 6994, pp. 834-40, 2004 (PubMed).

Alternatives for antigen "Der1-Like Domain Family, Member 2 (DERL2)", type "Antibodies"
Hosts (18)
Reactivities (14), (6)
Applications (18), (7), (7), (3), (2), (1)
Epitopes (13), (2), (2), (1), (1), (1), (1), (1)
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