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Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

Details for Product No. ABIN965991
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Antigen
Synonyms
zgc:110436, DERLIN-2.2, T4B21.2, T4B21_2, DERLIN-2.1, T8O5.20, T8O5_20, DDBDRAFT_0186360, DDBDRAFT_0266773, DDB_0186360, DDB_0266773, derl2, CG14899, Cg14899, DER1, Dmel\\CG14899, BC005682, CGI-101, D ... show more
zgc:110436, DERLIN-2.2, T4B21.2, T4B21_2, DERLIN-2.1, T8O5.20, T8O5_20, DDBDRAFT_0186360, DDBDRAFT_0266773, DDB_0186360, DDB_0266773, derl2, CG14899, Cg14899, DER1, Dmel\\CG14899, BC005682, CGI-101, Derlin-2, F-lana, Flana, RP23-83I13.8, F-LAN-1, F-LANa, FLANa show less
Epitope
N-Term
(23), (7), (1), (1)
Reactivity
Human, Mouse (Murine)
(21), (9)
Host
Rabbit
(28)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(28), (22), (7), (2), (1), (1)
Pubmed 3 references available
Quantity 0.1 mg
Options
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Catalog No. ABIN965991
316.25 $
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name DERL2
Background DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.
Research Area Signaling
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Lai, Chou, Chang et al.: "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." in: Genome research, Vol. 10, Issue 5, pp. 703-13, 2000 (PubMed).

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, 2001 (PubMed).

Lilley, Ploegh: "A membrane protein required for dislocation of misfolded proteins from the ER." in: Nature, Vol. 429, Issue 6994, pp. 834-40, 2004 (PubMed).

Validation Images
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