Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

Antigen: Der1-Like Domain Family, Member 2 (DERL2)

Synonyms: FLANa, F-LANa, CGI-101, F-LAN-1, Flana, F-lana, BC005682, Derlin-2, MGC11613, RP23-83I13.8, DERL2, MGC127058, DERLIN-2.2, T4B21.2, T4B21_2, DERLIN-2.1, T8O5.20, T8O5_20, DKFZp459O0332, derl2, CG14899, DER1, DmelCG14899

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine)

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN965991

Additional Information

Alternative name: DERL2

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)

Description: DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Synonyms: FLANa, F-LANa, CGI-101, F-LAN-1, Flana, F-lana, BC005682, Derlin-2, MGC11613, RP23-83I13.8, DERL2, MGC127058, DERLIN-2.2, T4B21.2, T4B21_2, DERLIN-2.1, T8O5.20, T8O5_20, DKFZp459O0332, derl2, CG14899, DER1, DmelCG14899

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Purification: Purified by antigen-specific affinity chromatography.

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: 0.01% Sodium Azide

Storage: Store at -20°C.

Research Area: Signaling

Restrictions: For Research Use only

Publications

Product: Lai, Chou, Chang et al.: "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." in: Genome research, Vol. 10, Issue 5, pp. 703-13, 2000 (PubMed).

Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, 2001 (PubMed).

Lilley, Ploegh: "A membrane protein required for dislocation of misfolded proteins from the ER." in: Nature, Vol. 429, Issue 6994, pp. 834-40, 2004 (PubMed).