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Der1-Like Domain Family, Member 2 (DERL2) (N-Term) antibody

Details for Product No. ABIN965991, Supplier: Login to see
Antigen
  • zgc:110436
  • DERLIN-2.2
  • T4B21.2
  • T4B21_2
  • DERLIN-2.1
  • T8O5.20
  • T8O5_20
  • DDBDRAFT_0186360
  • DDBDRAFT_0266773
  • DDB_0186360
  • DDB_0266773
  • derl2
  • CG14899
  • Cg14899
  • DER1
  • Dmel\\CG14899
  • BC005682
  • CGI-101
  • Derlin-2
  • F-lana
  • Flana
  • RP23-83I13.8
  • F-LAN-1
  • F-LANa
  • FLANa
Epitope
N-Term
39
16
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
28
21
Host
Rabbit
46
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
Immunohistochemistry (IHC)
43
33
5
5
4
2
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DERL2 (Derlin-2)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name DERL2 (DERL2 Antibody Abstract)
Background DERL2 (Derlin-2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.
Research Area Signaling
Pathways
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Ying, Yu, Xu: "Cloning and characterization of F-LANa, upregulated in human liver cancer." in: Biochemical and biophysical research communications, Vol. 286, Issue 2, pp. 394-400, 2001 (PubMed).

Background publications Lilley, Ploegh: "A membrane protein required for dislocation of misfolded proteins from the ER." in: Nature, Vol. 429, Issue 6994, pp. 834-40, 2004 (PubMed).

Lai, Chou, Chang et al.: "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." in: Genome research, Vol. 10, Issue 5, pp. 703-13, 2000 (PubMed).