EIF4E antibody

Catalog No. ABIN966057

Product Details anti-EIF4E Antibody

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4E antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: ElF4E (Ab-209) antibody detects endogenous levels of total elF4E protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human elF4E around the phosphorylation site of serine 209 (S-G-SP-T-T).

Application Details

Application Notes: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-EIF4E antibody (ABIN966057)

Gu, Li, Zhao, Fang, Bu, Frazer, Zhao: "tRNASer(CGA) differentially regulates expression of wild-type and codon-modified papillomavirus L1 genes." in: Nucleic acids research, Vol. 32, Issue 15, pp. 4448-61, (2004) (PubMed).

Li, McDonald, Nassar, De Benedetti: "Clinical outcome in stage I to III breast carcinoma and eIF4E overexpression." in: Annals of surgery, Vol. 227, Issue 5, pp. 756-6l; discussion 761-3, (1998) (PubMed).

Ohlmann, Rau, Pain, Morley: "The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E." in: The EMBO journal, Vol. 15, Issue 6, pp. 1371-82, (1996) (PubMed).

Target Details for EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Abstract: EIF4E Products

Pathways: BCR Signaling