HspX (N-Term) antibody

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Mycobacterium tuberculosis (M. tuberculosis )
Immunohistochemistry (IHC)
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of Bacteria Mycobacterium tuberculosis HSPX (heat shock protein hspX)
Background HSPX (heat shock protein hspX) functions as stress protein induced by anoxia. hspX has a proposed role in maintenance of long-term viability during latent, asymptomatic infections, and a proposed role in replication during initial infection. regulated by the two component regulatory system devr|rv3133c/devs|rv3132c, in response to a hypoxic signal. The hspX contains a ACD_sHsps-like domain. Alpha-crystallin domain (ACD) of alpha-crystallin- type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD).
Restrictions For Research Use only
Product cited in: Garnier, Eiglmeier, Camus, Medina, Mansoor, Pryor, Duthoy, Grondin, Lacroix, Monsempe, Simon, Harris, Atkin, Doggett, Mayes, Keating, Wheeler, Parkhill, Barrell, Cole, Gordon, Hewinson: "The complete genome sequence of Mycobacterium bovis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 13, pp. 7877-82, 2003 (PubMed).

Cole, Brosch, Parkhill, Garnier, Churcher, Harris, Gordon, Eiglmeier, Gas, Barry, Tekaia, Badcock, Basham, Brown, Chillingworth, Connor, Davies, Devlin, Feltwell, Gentles, Hamlin, Holroyd, Hornsby et al.: "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. ..." in: Nature, Vol. 393, Issue 6685, pp. 537-44, 1998 (PubMed).