Integrin alpha V (ITGAV) (C-Term) antibody

Details for Product No. ABIN966421
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Antigen
Synonyms CD51, MSK8, VNRA, VTNR, 1110004F14Rik, 2610028E01Rik, D430040G12Rik, Cd51
Epitope
C-Term
(9), (4), (4), (3), (3), (2), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Chicken
(137), (79), (40), (35), (34), (34), (23), (1), (1), (1), (1)
Host
Rabbit
(81), (61), (35), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(18), (13), (13), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(130), (52), (46), (29), (29), (20), (20), (16), (16), (14), (13), (3), (3), (3), (2), (1), (1), (1)
Pubmed 4 references available
Catalog no. ABIN966421
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 5 to 7 Business Days

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ITGAV (Integrin alpha-V precursor)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name ITGAV
Background The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-V contains the heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit.
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Suzuki, Argraves, Pytela et al.: "cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 22, pp. 8614-8, 1986 (PubMed).

Xiong, Stehle, Diefenbach et al.: "Crystal structure of the extracellular segment of integrin alpha Vbeta3." in: Science (New York, N.Y.), Vol. 294, Issue 5541, pp. 339-45, 2001 (PubMed).

Zhang, Li, Martin et al.: "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry." in: Nature biotechnology, Vol. 21, Issue 6, pp. 660-6, 2003 (PubMed).

Krokhin, Cheng, Sousa et al.: "Mass spectrometric based mapping of the disulfide bonding patterns of integrin alpha chains." in: Biochemistry, Vol. 42, Issue 44, pp. 12950-9, 2003 (PubMed).

Hosts (81), (61), (35), (1)
Reactivities (137), (79), (40), (35), (34), (34), (23), (1), (1), (1), (1)
Applications (130), (52), (46), (29), (29), (20), (20), (16), (16), (14), (13), (3), (3), (3), (2), (1), (1), (1)
Conjugates (18), (13), (13), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (9), (4), (4), (3), (3), (2), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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