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Integrin alpha V (ITGAV) (C-Term) antibody

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Antigen
Synonyms CD51, MSK8, VNRA, VTNR, 1110004F14Rik, 2610028E01Rik, D430040G12Rik, Cd51
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human, Mouse (Murine), Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 4 references available
Catalog no. ABIN966421
Quantity 0.1mg
Price
357.50 $   Plus shipping costs $45.00
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Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ITGAV (Integrin alpha-V precursor)
Purification Purified by antigen-specific affinity chromatography.

Target Details

Application Details Handling References Alternatives back to top
Alternative Name ITGAV
Background The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-V contains the heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit.

Application Details

Target Details Handling References Alternatives back to top
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Buffer This antibody is stored in PBS, 50% glycerol
Preservative 0.01% Sodium Azide
Storage -20 °C

References

Target Details Application Details Handling Alternatives back to top
Product cited in: Suzuki, Argraves, Pytela et al.: "cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 22, pp. 8614-8, 1986 (PubMed).

Xiong, Stehle, Diefenbach et al.: "Crystal structure of the extracellular segment of integrin alpha Vbeta3." in: Science (New York, N.Y.), Vol. 294, Issue 5541, pp. 339-45, 2001 (PubMed).

Zhang, Li, Martin et al.: "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry." in: Nature biotechnology, Vol. 21, Issue 6, pp. 660-6, 2003 (PubMed).

Krokhin, Cheng, Sousa et al.: "Mass spectrometric based mapping of the disulfide bonding patterns of integrin alpha chains." in: Biochemistry, Vol. 42, Issue 44, pp. 12950-9, 2003 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "Integrin alpha V (ITGAV)", type "Antibodies"
Hosts (75), (52), (22), (1)
Reactivities (124), (64), (38), (18), (18), (18), (17), (17), (6), (1), (1)
Applications (114), (49), (47), (32), (22), (22), (14), (13), (12), (10), (7), (6), (3), (2), (1)
Conjugates (18), (15), (10), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (40), (4), (4), (3), (1)
Beacon
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