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Kelch-Like 15 (Drosophila) (KLHL15) (C-Term) antibody

Details for Product No. ABIN966458, Supplier: Login to see
Antigen
  • 6330500C13Rik
  • wu:fa66h10
  • zgc:101051
  • RGD1563101
Epitope
C-Term
11
1
1
Reactivity
Human, Mouse (Murine)
20
11
11
1
1
Host
Rabbit
20
Clonality
Polyclonal
Application
Immunohistochemistry (IHC)
20
11
7
5
4
4
2
2
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human KLHL15 ( Kelch-like protein 15)
Alternative Name KLHL15 (KLHL15 Antibody Abstract)
Background KLHL15 ( Kelch-like protein 15) is a member of the kelch-like family of proteins that share a common domain structure consisting of an N-terminal broad-complex, tramtrack, bric-abrac/poxvirus and zinc finger domain and C-terminal kelch repeat motifs. KLHL15 is probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. KLHL15 interacts with CUL3 and contains 1 BACK (BTB/Kelch associated) domain, 1 BTB (POZ) domain and 5 Kelch repeats.
Synonyms: KIAA1677
Research Area Proteolysis / Ubiquitin
Pathways
Restrictions For Research Use only
Product cited in: Yoshida: "Identification and characterization of a novel kelch-like gene KLHL15 in silico." in: Oncology reports, Vol. 13, Issue 6, pp. 1133-7, 2005 (PubMed).

Furukawa, He, Borchers et al.: "Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases." in: Nature cell biology, Vol. 5, Issue 11, pp. 1001-7, 2003 (PubMed).

Background publications Bechtel, Rosenfelder, Duda et al.: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, 2008 (PubMed).

Nagase, Kikuno, Hattori et al.: "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 7, Issue 6, pp. 347-55, 2001 (PubMed).