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Details for Product No. ABIN966586

Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10) (C-Term), (AA 410-422) antibody

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Antigen
Synonyms SL-2, MMP-10, AV377895, STMY2
Epitope
»Alternatives C-Term, AA 410-422
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN966586
Quantity 100 µg
Price
316.25 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human MMP-10 (410-422 aa), identical to the related mouse and rat sequence.
Alternative Name MMP-10
Background Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Research Area Extracellular Matrix
Application Notes WB: The detection limit for MMP-10 is approximately 2.5ng/lane under non-reducing and reducing conditions.
Restrictions For Research Use only
Reconstitution 0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative Thimerosal (Merthiolate), Sodium azide
Storage -20 °C
Product cited in: Jung, Warter, Rumpler: "Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization." in: Annales de génétique, Vol. 33, Issue 1, pp. 21-3, 1990 (PubMed).

Muller, Quantin, Gesnel et al.: "The collagenase gene family in humans consists of at least four members." in: The Biochemical journal, Vol. 253, Issue 1, pp. 187-92, 1988 (PubMed).

Alternatives for antigen "Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10)", type "Antibodies"
Hosts (72), (10)
Reactivities (81), (25), (21)
Applications (44), (34), (29), (14), (11), (10), (10), (6), (2), (2), (2), (1), (1)
Conjugates (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1)
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