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Details for Product No. ABIN966593

Mps1 antibody

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Synonyms 2610507N02Rik, AI326283, B930008N24Rik, TTK, Ttbk, Ttbk1, mKIAA0847, AL022661, Esk1, Mps1, PYT, esk, CT96, ESK, MPH1, MPS1, MPS1L1
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Immunofluorescence (IF), ELISA
Pubmed 3 references available
Catalog no. ABIN966593
Quantity 0.1 mL
426.25 $   Plus shipping costs $45.00
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Immunogen Purified recombinant fragment of MPS1 expressed in E. Coli.
Clone 7E3
Isotype IgG1
Purification Ascitic fluid
Background MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms: RPS27
Molecular Weight 95kDa
Gene ID 6232
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Preservative Sodium azide
Storage 4 °C
Product cited in: Wool, Chan, Glück: "Structure and evolution of mammalian ribosomal proteins." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 73, Issue 11-12, pp. 933-47, 1996 (PubMed).

Liu, Chan, Hittle et al.: "Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores." in: Molecular biology of the cell, Vol. 14, Issue 4, pp. 1638-51, 2003 (PubMed).

Jelluma, Brenkman, van den Broek et al.: "Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment." in: Cell, Vol. 132, Issue 2, pp. 233-46, 2008 (PubMed).

Alternatives for antigen "Mps1", type "Antibodies"
Hosts (37), (24), (1)
Reactivities (62), (22), (13), (11), (11), (11)
Applications (34), (33), (21), (9), (6), (5), (5), (5), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (5), (4), (3), (2), (2), (2), (1), (1)