Neurogenin 3 (NEUROG3) antibody

Details for Product No. ABIN966645
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Antigen
Synonyms NEUROG3, ngn3, atoh5, ngn-3, bhlha7, math4b, neurog3, Ngn3, Atoh5, Math4B, NGN-3, bHLHa7, Relax, atoh4, ngn2, ngn3a
Reactivity
Human
(69), (23), (14), (13), (13), (2), (1)
Host
Mouse
(50), (24), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(56), (32), (21), (10), (7), (7), (6), (4), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
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Catalog No. ABIN966645
385.00 $
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Immunogen Purified recombinant fragment of human Neurogenin-3 expressed in E. Coli.
Clone 6G2
Isotype IgG1
Purification Liquid
Alternative Name Neurogenin-3
Background Neurogenin-3 (NEUROG3), also known as NGN3, it is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine. It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm.
Synonyms: ngn3, Atoh5, Math4B, bHLHa7, NEUROG3
Molecular Weight 23kDa
Gene ID 50674
Application Notes Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Heremans, Van De Casteele, int Veld et al.: "Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3." in: The Journal of cell biology, Vol. 159, Issue 2, pp. 303-12, 2002 (PubMed).

Gradwohl, Dierich, LeMeur et al.: "neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 4, pp. 1607-11, 2000 (PubMed).

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