Add to Basket Bulk discount
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

S100 Calcium Binding Protein A1 (S100A1) antibody

Antigen

S100 Calcium Binding Protein A1 (S100A1)
Synonyms S100, S100A, S100-alpha, S100a1, S100A1, MGC159706, DKFZp468K0511
Clonality Monoclonal
Host
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA
3 references available
Catalog no. ABIN966986
Quantity 0.1ml
Price 426.25 $   Plus shipping costs $45.00
Bulk discount
Shipping to
Availability Will be delivered in 5 to 7 Business Days

Additional Information
Application Details Publications Alternatives back to top

Alternative name S100A
Gene ID 6271
Isotype IgG1
Description S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Specificity Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3)

Application Details
Publications Alternatives back to top

Application Notes Dilution ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test.
Purification Antibodies are purified by protein A affinity chromatography
Storage Store at -20° C.
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Pingerelli, Mizukami, Wagner et al.: "Investigation of the Ca2(+)-dependent interaction of trifluoperazine with S100a: a 19F NMR and circular dichroism study." in: Journal of protein chemistry, Vol. 9, Issue 2, pp. 169-75, 1990 (PubMed).

Hoyaux, Decaestecker, Heizmann et al.: "S100 proteins in Corpora amylacea from normal human brain." in: Brain research, Vol. 867, Issue 1-2, pp. 280-8, 2000 (PubMed).

Koenig, Wojcieszyn, Weeks et al.: "Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma." in: Veterinary pathology, Vol. 38, Issue 4, pp. 427-35, 2001 (PubMed).