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Tripartite Motif Containing 22 (TRIM22) (C-Term) antibody

Details for Product No. ABIN967202
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Synonyms GPSTAF50, RNF94, STAF50
(10), (7), (3), (2), (1), (1)
(37), (3)
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (IHC)
(30), (13), (10), (8), (4), (2), (2), (1)
Pubmed 7 references available
Quantity 0.1 mg
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Catalog No. ABIN967202
452.38 $
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human TRIM22 (Tripartite motif-containing protein 22)
Alternative Name TRIM22
Background TRIM22 (Tripartite motif-containing protein 22) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
Synonyms: RNF94 (RING finger protein 94), STAF50 (50 kDa-stimulated trans-acting factor)
Restrictions For Research Use only
Product cited in: Tissot, Mechti: "Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14891-8, 1995 (PubMed).

Reymond, Meroni, Fantozzi et al.: "The tripartite motif family identifies cell compartments." in: The EMBO journal, Vol. 20, Issue 9, pp. 2140-51, 2001 (PubMed).

Obad, Brunnström, Vallon-Christersson et al.: "Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells." in: Oncogene, Vol. 23, Issue 23, pp. 4050-9, 2004 (PubMed).

Duan, Gao, Xu et al.: "Identification of TRIM22 as a RING finger E3 ubiquitin ligase." in: Biochemical and biophysical research communications, Vol. 374, Issue 3, pp. 502-6, 2008 (PubMed).

Herr, Dressel, Walter: "Different subcellular localisations of TRIM22 suggest species-specific function." in: Immunogenetics, Vol. 61, Issue 4, pp. 271-80, 2009 (PubMed).

Eldin, Papon, Oteiza et al.: "TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus." in: The Journal of general virology, Vol. 90, Issue Pt 3, pp. 536-45, 2009 (PubMed).

Sivaramakrishnan, Sun, Rajmohan et al.: "B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies." in: FEBS letters, Vol. 583, Issue 12, pp. 2093-9, 2009 (PubMed).

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