Tripartite Motif Containing 22 (TRIM22) (N-Term) antibody

Details for Product No. ABIN967203
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Antigen
Synonyms GPSTAF50, RNF94, STAF50
Epitope
N-Term
(17), (15), (6), (3), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(60), (2), (2)
Host
Rabbit
(50), (10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(46), (21), (11), (10), (5), (3), (2), (2), (2), (1), (1)
Pubmed 7 references available
Quantity 0.1 mg
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM22 (Tripartite motif-containing protein 22)
Alternative Name TRIM22 (TRIM22 Antibody Abstract)
Background TRIM22 (Tripartite motif-containing protein 22) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
Synonyms: RNF94 (RING finger protein 94), STAF50 (50 kDa-stimulated trans-acting factor)
Restrictions For Research Use only
Product cited in: Sivaramakrishnan, Sun, Rajmohan et al.: "B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies." in: FEBS letters, Vol. 583, Issue 12, pp. 2093-9, 2009 (PubMed).

Eldin, Papon, Oteiza et al.: "TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus." in: The Journal of general virology, Vol. 90, Issue Pt 3, pp. 536-45, 2009 (PubMed).

Herr, Dressel, Walter: "Different subcellular localisations of TRIM22 suggest species-specific function." in: Immunogenetics, Vol. 61, Issue 4, pp. 271-80, 2009 (PubMed).

Duan, Gao, Xu et al.: "Identification of TRIM22 as a RING finger E3 ubiquitin ligase." in: Biochemical and biophysical research communications, Vol. 374, Issue 3, pp. 502-6, 2008 (PubMed).

Obad, Brunnström, Vallon-Christersson et al.: "Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells." in: Oncogene, Vol. 23, Issue 23, pp. 4050-9, 2004 (PubMed).

Reymond, Meroni, Fantozzi et al.: "The tripartite motif family identifies cell compartments." in: The EMBO journal, Vol. 20, Issue 9, pp. 2140-51, 2001 (PubMed).

Tissot, Mechti: "Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14891-8, 1995 (PubMed).

Validation Images
Catalog No. ABIN967203
466.13 $
Plus shipping costs $45.00
Quantity
Price
0.1 mg
466.13 $

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