TRIM22 antibody (N-Term)

Catalog No. ABIN967203

Product Details anti-TRIM22 Antibody

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM22 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM22 (Tripartite motif-containing protein 22)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-TRIM22 antibody (ABIN967203)

Sivaramakrishnan, Sun, Rajmohan, Lin: "B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies." in: FEBS letters, Vol. 583, Issue 12, pp. 2093-9, (2009) (PubMed).

Herr, Dressel, Walter: "Different subcellular localisations of TRIM22 suggest species-specific function." in: Immunogenetics, Vol. 61, Issue 4, pp. 271-80, (2009) (PubMed).

Eldin, Papon, Oteiza, Brocchi, Lawson, Mechti: "TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus." in: The Journal of general virology, Vol. 90, Issue Pt 3, pp. 536-45, (2009) (PubMed).

Duan, Gao, Xu, Xiong: "Identification of TRIM22 as a RING finger E3 ubiquitin ligase." in: Biochemical and biophysical research communications, Vol. 374, Issue 3, pp. 502-6, (2008) (PubMed).

Obad, Brunnström, Vallon-Christersson, Borg, Drott, Gullberg: "Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells." in: Oncogene, Vol. 23, Issue 23, pp. 4050-9, (2004) (PubMed).

Tissot, Mechti: "Molecular cloning of a new interferon-induced factor that represses human immunodeficiency virus type 1 long terminal repeat expression." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14891-8, (1995) (PubMed).

Target Details for TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Alternative Name: TRIM22 (TRIM22 Products)

Background: TRIM22 (Tripartite motif-containing protein 22) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
Synonyms: RNF94 (RING finger protein 94), STAF50 (50 kDa-stimulated trans-acting factor)