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YES1 antibody (AA 10-193)

YES1 Reactivity: Human, Mouse, Rat, Dog, Chicken WB, IHC, IF Host: Mouse Monoclonal 1-Yes unconjugated
Catalog No. ABIN967926
  • Target See all YES1 Antibodies
    YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))
    Binding Specificity
    • 17
    • 16
    • 16
    • 15
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 10-193
    Reactivity
    • 99
    • 48
    • 22
    • 3
    • 1
    • 1
    Human, Mouse, Rat, Dog, Chicken
    Host
    • 94
    • 7
    Mouse
    Clonality
    • 95
    • 5
    Monoclonal
    Conjugate
    • 34
    • 10
    • 9
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This YES1 antibody is un-conjugated
    Application
    • 95
    • 42
    • 39
    • 26
    • 22
    • 17
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus), Chicken, Dog (Canine)
    Characteristics
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Please refer to us for technical protocols.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human Yes aa. 10-193
    Clone
    1-Yes
    Isotype
    IgG1
    Top Product
    Discover our top product YES1 Primary Antibody
  • Comment

    Related Products: ABIN968533, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store undiluted at -20°C.
  • Chen, Lu, Goodenough, Jeansonne: "Nonreceptor tyrosine kinase c-Yes interacts with occludin during tight junction formation in canine kidney epithelial cells." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1227-37, (2002) (PubMed).

    Lee, Bonnah, Higashi, Atkinson, Milgram, So: "CD46 is phosphorylated at tyrosine 354 upon infection of epithelial cells by Neisseria gonorrhoeae." in: The Journal of cell biology, Vol. 156, Issue 6, pp. 951-7, (2002) (PubMed).

    Encinas, Tansey, Tsui-Pierchala, Comella, Milbrandt, Johnson: "c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 5, pp. 1464-72, (2001) (PubMed).

    Arizmendi, Family, Salas-Brito: "Quenched disorder effects on deterministic inertia ratchets." in: Physical review. E, Statistical, nonlinear, and soft matter physics, Vol. 63, Issue 6 Pt 1, pp. 61104, (2001) (PubMed).

    Park, Cartwright: "Src activity increases and Yes activity decreases during mitosis of human colon carcinoma cells." in: Molecular and cellular biology, Vol. 15, Issue 5, pp. 2374-82, (1995) (PubMed).

    Sukegawa, Semba, Yamanashi, Nishizawa, Miyajima, Yamamoto, Toyoshima: "Characterization of cDNA clones for the human c-yes gene." in: Molecular and cellular biology, Vol. 7, Issue 1, pp. 41-7, (1987) (PubMed).

  • Target
    YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))
    Alternative Name
    Yes (YES1 Products)
    Synonyms
    HsT441 antibody, P61-YES antibody, Yes antibody, c-yes antibody, yes antibody, p61-Yes antibody, hst441 antibody, p61-yes antibody, YES antibody, c-Yes antibody, p60c-yes antibody, YES proto-oncogene 1, Src family tyrosine kinase antibody, YES proto-oncogene 1, Src family tyrosine kinase L homeolog antibody, YES1 antibody, yes1.L antibody, yes1 antibody, Yes1 antibody
    Background
    Yes is a member of the Src family of tyrosine kinases. The cellular gene was initially identified as a homologue of v-yes, the oncogene of avian sarcoma virus Y73. At least nine different Src family members have been identified. yes, fyn, and Src are widely expressed in a variety of cell types, while the remaining members are primarily expressed in hematopoietic cells. Members of this family have several common features: they have unique N-terminal domains, they attach to cellular membranes through a myristylated N-terminus and they have homologus SH2, SH3, and catalytic domains. The common expression patterns of Yes, fyn, and Src suggest some overlapping functions. All three of these kinases can physically associate with a number of cell-surface molecules which appear to increase their catalytic activity.
    Molecular Weight
    62 kDa
    Pathways
    CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
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