X-Linked Inhibitor of Apoptosis (XIAP) (AA 268-426) antibody

Details for Product No. ABIN968163
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms BIRC4, api3, birc4, ilp1, miha, xlp2, xxiap, API3, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3, 1110015C02Rik, Aipa, Api3, Birc4, IAP3, ILP-1, mXIAP, riap3
AA 268-426
(26), (23), (12), (8), (7), (5), (5), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(154), (49), (35), (4), (2), (1)
(141), (18), (1)
Clonality (Clone)
Monoclonal ()
(5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
(141), (55), (54), (34), (18), (11), (10), (8), (8), (5), (4), (3), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 50 μg
Shipping to United States (Change)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN968163
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Human hILP
Clone CE6
Isotype IgG1
Cross-Reactivity Rat (Rattus), Mouse (Murine), Frog
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
Purification Purified from tissue culture supernatant or ascites by affinity chromatography.
Alternative Name hILP
Background Apoptosis is a genetically programmed, selective process of cell death that occurs during normal cell differentiation and development of multicellular organisms. Viruses depend on the biosynthetic machinery of their host cell for the production of progeny and survival. Therefore, many viruses encode proteins that protect the cell from apoptosis. hILP (human IAP-like protein) is a human homologue of the viral IAP (Inhibitor of Apoptosis Protein). hILP is a widely expressed cytoplasmic protein of 497 amino acids with three BIR (Baculovirus IAP repeats) domains and a C-terminal RING finger domain. hILP-transfected cells are protected against the apoptotic effects of Sindbis virus infection and ICE (interleukin-1beta converting enzyme) expression. This product is sold under license from Aegera Therapeutics, Inc. This antibody is routinely tested by western blot analysis.
Synonyms: hILP
Molecular Weight 57 kDa

Related Products: ABIN968537, ABIN967389

Restrictions For Research Use only
Format Liquid
Concentration 250 µg/ml
Buffer Aqueous buffered solution containing BSA, glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 268-426) antibody Immunofluorescent staining of Rabbit Liver tissue with anti-XIAP
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 268-426) antibody (2) Western blot analysis of hILP/XIAP on Jurkat lysate. Lane 1: 1:4000, lane 2: 1:8000, lane 3: 1:12000 dilution of anti-XIAP.
Product cited in: Deng, Lin, Wu: "TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO." in: Genes & development, Vol. 16, Issue 1, pp. 33-45, 2002 (PubMed).

Martins, Iaccarino, Tenev et al.: "The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 439-44, 2002 (PubMed).

Fulda, Meyer, Debatin: "Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression." in: Cancer research, Vol. 60, Issue 14, pp. 3947-56, 2000 (PubMed).

Tamm, Kornblau, Segall et al.: "Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 6, Issue 5, pp. 1796-803, 2000 (PubMed).

Duckett, Nava, Gedrich et al.: "A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors." in: The EMBO journal, Vol. 15, Issue 11, pp. 2685-94, 1996 (PubMed).

Validation Images
Did you look for something else?
back to top