Bone Morphogenetic Protein 4 (BMP4) antibody

Details for Product No. ABIN968986
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Antigen
Synonyms
bmp-4, zbmp-4, zgc:100779, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4, bmp-2, bmp2, bmp2-4, cb670, zbmp-2, zbmp2, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, Bmp-4, Bmp2b, Bmp2b-1, Bmp2b1, BOMPR4A, ... show more
bmp-4, zbmp-4, zgc:100779, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4, bmp-2, bmp2, bmp2-4, cb670, zbmp-2, zbmp2, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME, Bmp-4, Bmp2b, Bmp2b-1, Bmp2b1, BOMPR4A, BMP-4 show less
Reactivity
Human
(114), (35), (32), (11), (9), (9), (4), (3), (3), (1)
Host
Mouse
(114), (32), (4), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(10), (6), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(113), (63), (43), (32), (25), (15), (12), (10), (6), (5), (3), (2), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 100 μL
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Catalog No. ABIN968986
363.00 $
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Immunogen Purified recombinant fragment of human BMP4 expressed in E. coli.
Clone 10F4B4
Isotype IgG1
Purification Ascites
Alternative Name BMP4
Background Synonyms:
ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, BMP4
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-β superfamily. The superfamily includes large families of growth and differentiation factors. BMPs (bone morphogenetic proteins) belong to the TGF β superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF β superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
Molecular Weight 64 kDa
Gene ID 652
Research Area Organogenesis, Growth Factors, Angiogenesis, Signaling
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Bone Morphogenetic Protein 4 (BMP4) antibody Figure 1: Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate.
Product cited in: Oida, Iimura, Maruoka et al.: "Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 5, Issue 5, pp. 273-5, 1995 (PubMed).

Solmesky, Abekasis, Bulvik et al.: "Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium." in: Stem cells and development, Vol. 18, Issue 9, pp. 1283-92, 2009 (PubMed).

Validation Images
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