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Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody

Antigen

Chromodomain Helicase DNA Binding Protein 3 (CHD3)
Synonyms ZFH, Mi-2a, Mi2-ALPHA, Chd7, Prp7, Prp9-1, AF020312, MGC40857, 2600010P09Rik, CHD3, LOC568230, zfh, mi-2a, mi2-alpha
Clonality Monoclonal (2G4)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human, Mouse (Murine)
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB)
1 reference available
Catalog no. ABIN969052
Quantity 0.1ml  (Variants)
Price 363.00 $   Plus shipping costs $45.00
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name CHD3
Gene ID 1107
Immunogen Purified recombinant fragment of human CHD3 expressed in E. Coli.
Format Liquid
Isotype IgG1
Clone 2G4
Description This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Synonyms: ZFH, Mi-2a, Mi2-ALPHA, CHD3
Molecular Weight 226kDa

Application Details
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Application Notes Western Blotting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Purification Ascites
Buffer Ascitic fluid containing 0.03% sodium azide.
Preservative 0.03% sodium azide
Storage Store at 4℃, for long term storage, store at -20℃.
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Burd, Kinyamu, Miller et al.: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, 2008 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Chromodomain Helicase DNA Binding Protein 3 (CHD3)", type "Antibodies"
Hosts Rabbit (22), Mouse (10)
Reactivities Human (30), Mouse (Murine) (20), Rat (Rattus) (17)
Applications Immunofluorescence (IF) (16), Western Blotting (WB) (13), ELISA (12), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Flow Cytometry (FACS) (3), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes AA 1575-1625 (1), AA 1641-1657 (1), AA 27-44 (1), AA 474-970 (1), C-Term (1)