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Details for Product No. ABIN969052

Chromodomain Helicase DNA Binding Protein 3 (CHD3) antibody

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Antigen
Synonyms ZFH, Mi-2a, Mi2-ALPHA, 2600010P09Rik, AF020312, Chd7, Prp7, Prp9-1, CG9594, CHD-3, CHD3, DmCHD3, Dmel\\CG9594, chd3, dCHD3, LOC568230, zfh, mi-2a, mi2-alpha
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
Pubmed 1 reference available
Catalog no. ABIN969052
Quantity 0.1 mg
Price
363.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human CHD3 expressed in E. coli.
Clone 2G4
Isotype IgG1
Purification Ascites
Alternative Name CHD3
Background Synonyms:
ZFH, Mi-2a, Mi2-α, CHD3
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Molecular Weight 226 kDa
Gene ID 1107
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Burd, Kinyamu, Miller et al.: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, 2008 (PubMed).

Alternatives for antigen "Chromodomain Helicase DNA Binding Protein 3 (CHD3)", type "Antibodies"
Hosts (20), (16)
Reactivities (34), (19), (12), (12), (12), (1)
Applications (20), (18), (9), (8), (7), (7), (6), (6), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1)
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