Fatty Acid Binding Protein 4, Adipocyte (FABP4) antibody

Details for Product No. ABIN969126
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Antigen
Synonyms LOC100223994, fabp11, zgc:103587, FABP4, MGC84940, fabp4, AP2, A-FABP, AFABP, ALBP, aP2, 422/aP2, ALBP/Ap2, Ap2, Lbpl, Albp, FABP3, FABP
Reactivity
Human
(154), (58), (45), (27), (24), (13), (2), (1)
Host
Mouse
(110), (53), (3), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application
ELISA, Western Blotting (WB)
(122), (81), (24), (20), (14), (11), (9), (7), (5), (5), (4), (3), (3), (1)
Pubmed 2 references available
Quantity 100 μL
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Catalog No. ABIN969126
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Immunogen Purified recombinant fragment of FABP4 expressed in E. coli.
Clone 9B8D
Isotype IgG1
Purification Ascites
Alternative Name FABP4
Background Synonyms:
aP2, A-FABP, FABP4
Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and mηbolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.
Molecular Weight 14 kDa
Gene ID 2167
Research Area Cell Cycle
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Fatty Acid Binding Protein 4, Adipocyte (FABP4) antibody Figure 1: Western blot analysis using FABP4 mouse mAb against FABP4-hIgGFc transfected HEK293 cell lysate.
Product cited in: Gericke, Smith, Moore et al.: "Adipocyte fatty acid-binding protein: interaction with phospholipid membranes and thermal stability studied by FTIR spectroscopy." in: Biochemistry, Vol. 36, Issue 27, pp. 8311-7, 1997 (PubMed).

Tuncman, Erbay, Hom et al.: "A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 6970-5, 2006 (PubMed).

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