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Kelch-Like 25 (Drosophila) (KLHL25) antibody

Details for Product No. ABIN969248
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Antigen
Synonyms klhl25, MGC147232, 2810402K13Rik, BC027373, Enc-1, ENC-2, ENC2, RGD1310815, Xencr-2, encr-2
Reactivity
Human
(44), (3), (3), (2), (2), (1)
Host
Mouse
(20), (15), (9)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
ELISA, Western Blotting (WB)
(44), (30), (7), (4), (2), (1)
Pubmed 1 reference available
Quantity 100 µL
Options
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Catalog No. ABIN969248
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Immunogen Purified recombinant fragment of human KLHL25 expressed in E. coli.
Clone 1B7
Isotype IgG2b
Purification Ascites
Alternative Name KLHL25
Background Synonyms:
ENC2, ENC-2, FLJ12587, FLJ45015, KLHL25
KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
Molecular Weight 65 kDa
Gene ID 64410
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
anti-Kelch-Like 25 (Drosophila) (KLHL25) antibody Figure 1: Western blot analysis using KLHL25 mAb against KLHL25 (AA: 2-230) -hIgGFc transfected HEK293 cell.
Product cited in: Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).

Validation Images
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