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Kelch-Like 25 (Drosophila) (KLHL25) antibody

Details for Product No. ABIN969248, Supplier: Login to see
Antigen
  • klhl25
  • MGC147232
  • 2810402K13Rik
  • BC027373
  • Enc-1
  • ENC-2
  • ENC2
  • RGD1310815
  • Xencr-2
  • encr-2
Reactivity
Human
68
17
17
4
2
1
Host
Mouse
45
12
11
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
54
35
11
10
6
5
4
3
1
Supplier
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Immunogen Purified recombinant fragment of human KLHL25 expressed in E. coli.
Clone 1B7
Isotype IgG2b
Purification Ascites
Alternative Name KLHL25
Background KLHL25 (ectoderm-neural cortex protein 2, ENC2) is a cytoplasmic protein that contains six Kelch regions and a single BTB (POZ) domain. KLHL25 is highly homologus to another Kelch-like protein, ENC1, and it is believed to operate in a manner similar to other Kelch-domain containing proteins. Kelch-domain repeat containing proteins often act as modifiers of Actin fibers. Expressed early in embryogenesis, ENC1 helps to mediate neuronal process formation. It also appears to have a role in neural crest cell differentiation. KLHL25 likely functions as a substrate specific adapter for protein ubiquitinating complexes. KLHL25 is expressed in most tissues with highest expression in brain and liver.
Molecular Weight 65 kDa
Gene ID 64410
HGNC 64410
Pathways
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Western Blotting (WB) image for anti-Kelch-Like 25 (Drosophila) (KLHL25) antibody (ABIN969248) Figure 1: Western blot analysis using KLHL25 mAb against KLHL25 (AA: 2-230) -hIgGFc t...
Product cited in: Lunetta, DAgostino, Karasik et al.: "Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study." in: BMC medical genetics, Vol. 8 Suppl 1, pp. S13, 2007 (PubMed).

Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).