Mps1 antibody

Details for Product No. ABIN969291
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Synonyms MPS1, Mpg-1, 2610507N02Rik, AI326283, B930008N24Rik, TTK, Ttbk, Ttbk1, mKIAA0847, CT96, ESK, MPH1, MPS1L1, PYT, AL022661, Esk1, Mps1, esk, mps1, ncp
(123), (30), (22)
(86), (31), (9), (2)
Clonality (Clone)
Monoclonal ()
(7), (7), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1)
ELISA, Immunocytochemistry (ICC)
(87), (76), (43), (10), (10), (10), (9), (6), (5), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 100 μL
Shipping to United States ( )
Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of MPS1 expressed in E. coli.
Clone 7-00E-03
Isotype IgG1
Purification Ascites
Background MPS1, also known as RPS27. It is a ribosomal protein. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. MPS1 is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Molecular Weight 95 kDa
Gene ID 6232
HGNC 6232
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Recommended Dilution:
ELISA: 1/10000, ICC: 1/200 - 1/1000
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
Immunocytochemistry (ICC) image for anti-Mps1 antibody (ABIN969291) Figure 1: Confocal immunofluorescence analysis of Hela cells (A), BCBL-1 cells (B) an...
Background publications Liu, Chan, Hittle et al.: "Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores." in: Molecular biology of the cell, Vol. 14, Issue 4, pp. 1638-51, 2003 (PubMed).

Wool, Chan, Glück: "Structure and evolution of mammalian ribosomal proteins." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 73, Issue 11-12, pp. 933-47, 1996 (PubMed).

Catalog No. ABIN969291
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