WNT10B antibody

Catalog No. ABIN969459

Product Details anti-WNT10B Antibody

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WNT10B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human WNT10B expressed in E. coli.

Clone: 5A7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-WNT10B antibody (ABIN969459)

Saitoh, Kirikoshi, Mine, Katoh: "Proto-oncogene WNT10B is up-regulated by tumor necrosis factor alpha in human gastric cancer cell line MKN45." in: International journal of oncology, Vol. 19, Issue 6, pp. 1187-92, (2001) (PubMed).

Target Details for WNT10B

Target: WNT10B (Wingless-Type MMTV Integration Site Family, Member 10B (WNT10B))

Alternative Name: WNT10B (WNT10B Products)

Synonyms: WNT10B antibody, Xwnt-10b antibody, Xwnt10b antibody, wnt-12 antibody, Wnt12 antibody, SHFM6 antibody, WNT-12 antibody, Xwnt-10 antibody, wnt10 antibody, wnt10-A antibody, Zwnt[d] antibody, wnt10br antibody, wnt[d] antibody, Wnt family member 10B antibody, wingless-type MMTV integration site family, member 10B antibody, Wnt family member 10B S homeolog antibody, wingless-type MMTV integration site family, member 10b antibody, WNT10B antibody, wnt10b antibody, Wnt10b antibody, wnt10b.S antibody

Background:

Description: WNT10B: wingless-type MMTV integration site family, member 10B. The WNT family consists of structurally related secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT10B is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is ikely a molecular switch that governs adipogenesis. This protein is 96 % identical to the mouse Wnt10B protein at the amino acid level. The WNT10B gene is clustered with another family member, WNT1, in the chromosome 12q13 region.

Aliases: SHFM6, WNT-12

Molecular Weight: 43 kDa

Gene ID: 7480

HGNC: 7480

Pathways: WNT Signaling, Skeletal Muscle Fiber Development