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Details for Product No. ABIN969539

Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody

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Antigen
Synonyms CHDS6, MMP-3, SL-1, STMY, STMY1, STR1, SLN1, Str1, SLN-1, STR-1, Stmy1
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Fluorescence Microscopy (FM)
Pubmed 2 references available
Catalog no. ABIN969539
Quantity 0.1 mg
Price
396.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 3 to 4 Business Days
Immunogen Purified recombinant fragment of human MMP3 expressed in E. coli.
Clone 4F10
Isotype IgG1
Purification Purified
Alternative Name MMP3
Background Synonyms:
SL-1, STMY, STR1, CHDS6, MMP-3, STMY1
Proteins of the matrix mηlloproteinase (MMP) family are involved in the breakDaown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and mηstasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
Molecular Weight 54 kDa
Gene ID 4314
Research Area Cardiovascular, Atherosclerosis, Proteolysis / Ubiquitin, Metalloprotease, Angiogenesis, Extracellular Matrix, Matrix Metalloproteinases
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Product cited in: Nan, Niu, Hunter et al.: "Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3551-7, 2008 (PubMed).

Jin, Miao, Hu et al.: "Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 2172-8, 2009 (PubMed).

Alternatives for antigen "Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3)", type "Antibodies"
Hosts (84), (57), (8), (8), (2)
Reactivities (145), (44), (37), (14), (13), (12), (9), (5), (1), (1)
Applications (122), (65), (56), (35), (32), (12), (12), (12), (10), (7), (5), (2), (2), (2)
Conjugates (9), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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