You are viewing an incomplete version of our website. Please click to reload the website as full version.

Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody

Details for Product No. ABIN969539, Supplier: Login to see
Antigen
  • SLN-1
  • SLN1
  • STR-1
  • Stmy1
  • Str1
  • CHDS6
  • MMP-3
  • SL-1
  • STMY
  • STMY1
  • STR1
  • MMP10
  • MMP3
Reactivity
Human
290
63
59
11
6
3
2
2
2
1
1
Host
Mouse
201
107
19
6
2
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
20
18
16
6
6
6
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
248
149
105
69
50
28
24
21
20
11
10
2
2
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen Purified recombinant fragment of human MMP3 expressed in E. coli.
Clone 4F10
Isotype IgG1
Purification Purified
Alternative Name MMP3 (MMP3 Antibody Abstract)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Molecular Weight 54 kDa
Gene ID 4314
HGNC 4314
Research Area Cardiovascular, Atherosclerosis, Proteolysis / Ubiquitin, Metalloprotease, Angiogenesis, Extracellular Matrix, Matrix Metalloproteinases
Pathways
Application Notes Recommended Dilution:
ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C or at -20 °C for long term.
Supplier Images
ELISA image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Flow Cytometry (FACS) image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and ...
Western Blotting (WB) image for anti-Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3) antibody (ABIN969539) Figure 3: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recom...
Product cited in: Jin, Miao, Hu et al.: "Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 9, pp. 2172-8, 2009 (PubMed).

Nan, Niu, Hunter et al.: "Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3551-7, 2008 (PubMed).