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Browse our ABL1 Proteins (ABL1)

Full name:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase Proteins (ABL1)
On www.antibodies-online.com are 0 C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Proteins from different suppliers available. A total of 0 ABL1 products are currently listed.
Synonyms:
Abl, ABL1, ABLL, AI325092, bcr/abl, c-Abl, CABL, cb272, E430008G22Rik, JTK7, MTP, p150, v-abl
list all proteins Gene Name GeneID UniProt
Human ABL1 ABL1 25 P00519
Mouse ABL1 ABL1 11350 P00520
Rat ABL1 ABL1 311860  

Show all synonyms

More Proteins for ABL1 Interaction Partners

Human C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. mammalian c-Abl plays an important role in steroid hormone receptor (show NR4A1 Proteins)-mediated transcription by regulating RBM39 (show RBM39 Proteins)

  2. demonstrated that depletion of endogenous MAPK15 (show MAPK15 Proteins) expression inhibited BCR (show BCR Proteins)-ABL1-dependent cell proliferation

  3. the N-terminal domain of MTP (show MT1B Proteins) is important for its lipid transfer activity

  4. By visually examining the dynamics behavior, structural basis and energetic property of few typical Abl-drug complex cases, a significantly different pattern of non-bonded interactions between the binding of drug ligands to Abl receptor was revealed.

  5. Identify a novel BCR-ABL/IkappaBalpha (show NFKBIA Proteins)/p53 (show TP53 Proteins) network, whereby BCR-ABL functionally inactivates a key tumor suppressor in chronic myeloid leukemia (show BCL11A Proteins).

  6. Blockade of the interaction between Bcr-Abl and PTB1B by small molecule SBF-1 to overcomes imatinib-resistance of K562 cells.

  7. BCR-ABL1 transcript types found in Syria were similar to that of Indian Far-Eastern, African or European populations. The M-BCR rearrangement types were not dependent on white blood count, platelet count, hemoglobin level or gender of the patients.

  8. Data suggest elevated interleukin-1beta secretion from tyrosine kinase (show TXK Proteins) inhibitor- (TKI-)resistant chronic myeloid leukemia (show BCL11A Proteins) (CML (show BCR Proteins)) cells contributes to TKI/imatinib resistance via promotion of cell viability/migration; cells used lack BCR-ABL mutation.

  9. Our results link FGF8 (show FGF8 Proteins), c-Abl and p300 (show EP300 Proteins) in a regulatory pathway that controls DeltaNp63alpha protein stability and transcriptional activity.

  10. Suggest that AIC-47 in combination with imatinib strengthened the attack on cancer energy metabolism in BCR-ABL-harboring leukemic cells.

Mouse (Murine) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. Our data show that: i) HDAC2 (show HDAC2 Proteins) levels and activity are increased in NPC (show NPC1 Proteins) neuronal models and in Npc1 (show NPC1 Proteins)(-/-) mice; ii) inhibition of c-Abl or c-Abl deficiency prevents the increase of HDAC2 (show HDAC2 Proteins) protein levels and activity in NPC (show NPC1 Proteins) neuronal models

  2. The resistance in BCR (show BCR Proteins)-ABL1 cells resulted either from the Y253H mutation in the BCR (show BCR Proteins)-ABL1 gene or incubation in increasing concentrations of imatinib.

  3. These results reveal a new pathway in the DNA damage response wherein ABL-dependent tyrosine phosphorylation of DGCR8 (show DGCR8 Proteins) stimulates the processing of selective primary miRNAs.

  4. These findings connect the EphB signaling pathway to the regulation of intestinal adenoma initiation via Abl kinase.

  5. overexpression of Id2 in primary alveolar epithelial cells promotes proliferation by inhibiting a retinoblastoma protein/c-Abl interaction leading to greater c-Abl activity.

  6. The study demonstrates a previously unrecognized mechanism that controls insulin (show INS Proteins) expression through c-Abl-regulated NKx2.2 (show Nkx2-2 Proteins) and GLUT2 (show SLC2A2 Proteins).

  7. Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.

  8. LPS-induced paxillin phosphorylation at Y31 and Y118 was mediated by c-Abl tyrosine kinase

  9. c-Abl modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity.

  10. Data (including data from mouse mutant strains) suggest that neuropilin-1 (show NRP1 Proteins) in vascular endothelium contributes to angiogenesis via VEGFA (show VEGFA Proteins)-independent mechanism involving Abl1 signaling in the extracellular matrix in VEGFA (show VEGFA Proteins)-independent mechanism. [REVIEW]

Caenorhabditis elegans (C. elegans) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. By screening candidate genes involved in Eph (show EPHA1 Proteins) signaling, we find that the Eph (show EPHA1 Proteins) kinase-independent pathway involves the ABL-1 nonreceptor tyrosine kinase (show TYRO3 Proteins) and possibly the phosphatidylinositol 3-kinase pathway

  2. The trade-off in immunological susceptibility in C. elegans is further mediated by the reciprocal activity of lys (show LYZ Proteins)-7 and the tyrosine kinase abl-1.

  3. oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 (show TP53 Proteins) and EGL-1 independent pathway; the MAPK (show MAPK1 Proteins) kinases MEK-1 (show MAP2K1 Proteins) and SEK-1 (show MAP2K4 Proteins), and the p53 (show TP53 Proteins) antagonist protein ABL-1, are essential for stress-induced germ cell apoptosis

  4. findings demonstrate that ABL-1, the C. elegans homolog of the mammalian c-Abl nonreceptor tyrosine kinase (show TYRO3 Proteins) ABL1, is required for Shigella flexneri pathogenesis in nematodes

ABL1 Protein Profile

Protein Summary

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Alternative names and synonyms associated with ABL1

  • c-abl oncogene 1, receptor tyrosine kinase (ABL1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (ABL1)
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2)
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (abl2)
  • c-abl oncogene 1, non-receptor tyrosine kinase (Abl1)
  • microsomal triglyceride transfer protein (MTTP)
  • Protein ABL-1 (abl-1)
  • Abl protein
  • ABL1 protein
  • ABLL protein
  • AI325092 protein
  • bcr/abl protein
  • c-Abl protein
  • CABL protein
  • cb272 protein
  • E430008G22Rik protein
  • JTK7 protein
  • MTP protein
  • p150 protein
  • v-abl protein

Protein level used designations for ABL1

c-abl oncogene 1, receptor tyrosine kinase , v-abl Abelson murine leukemia viral oncogene homolog 1 , Abelson murine leukemia viral (v-abl) oncogene homolog 1 , v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) , tyrosine kinase ABL , Abelson murine leukemia viral (v-abl) oncogene homolog 2 , Abelson tyrosine-protein kinase 2 , arg, Abelson-related , tyrosine-protein kinase ABL2 , v-abl Abelson murine leukemia viral oncogene homolog 2 , arg tyrosine kinase , tyrosine-protein kinase ABL2-like , Abelson tyrosine-protein kinase 1 , bcr/c-abl oncogene protein , proto-oncogene c-Abl , proto-oncogene tyrosine-protein kinase ABL1 , tyrosine-protein kinase ABL1 , Abelson murine leukemia oncogene , abelson murine leukemia viral oncogene homolog 1 , p150 , v-abl Abelson murine leukemia oncogene 1 , v-abl Abelson murine leukemia viral oncogene 1 , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein large subunit

GENE ID SPECIES
280970 Bos taurus
417181 Gallus gallus
464802 Pan troglodytes
491292 Canis lupus familiaris
395410 Gallus gallus
457552 Pan troglodytes
511845 Bos taurus
570636 Danio rerio
717037 Macaca mulatta
100348328 Oryctolagus cuniculus
100463896 Ailuropoda melanoleuca
100543723 Meleagris gallopavo
100588798 Nomascus leucogenys
25 Homo sapiens
540876 Bos taurus
11350 Mus musculus
311860 Rattus norvegicus
4547 Homo sapiens
181261 Caenorhabditis elegans
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