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Browse our ABL1 Proteins (ABL1)

Full name:
C-Abl Oncogene 1, Non-Receptor tyrosine Kinase Proteins (ABL1)
On are 26 C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Proteins from 8 different suppliers available. Additionally we are shipping ABL1 Antibodies (614) and ABL1 Kits (12) and many more products for this protein. A total of 709 ABL1 products are currently listed.
Abl, ABL1, ABLL, AI325092, bcr/abl, c-Abl, CABL, cb272, E430008G22Rik, JTK7, MTP, p150, v-abl
list all proteins Gene Name GeneID UniProt
ABL1 25 P00519
ABL1 11350 P00520
Rat ABL1 ABL1 311860  

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ABL1 Proteins (ABL1) by Origin

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Top referenced ABL1 Proteins

  1. Human ABL1 Protein expressed in Baculovirus infected Insect Cells - ABIN2004077 : Wisniewski, Strife, Swendeman, Erdjument-Bromage, Geromanos, Kavanaugh, Tempst, Clarkson et al.: A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic ... in Blood 1999 (PubMed)
    Show all 5 references for ABIN2004077

More Proteins for ABL1 Interaction Partners

Human C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. ETV6 (show ETV6 Proteins)-ABL1 fusion occurs in both lymphoid and myeloid leukemias; the genomic profile and clinical behavior resemble BCR (show BCR Proteins)-ABL1-positive malignancies, including the unfavorable prognosis, particularly of acute leukemias. The poor outcome suggests that treatment with tyrosine kinase (show TXK Proteins) inhibitors should be considered for patients with this fusion.

  2. the c-Abl non-receptor kinase phosphorylates DDB1 (show DDB1 Proteins) at residue Tyr (show TYR Proteins)-316 to recruit a small regulatory protein, DDA1 (show DDA1 Proteins), leading to increased substrate ubiquitination

  3. In chronic hepatitis C patients infected with HCV genotype 3 and with the TT/GT genotype of the MTTP (show MTTP Proteins) -493G/T SNP, a significant increase in hepatic steatosis was observed, which may indicate that this SNP has a significant influence on the accumulation of triglycerides in hepatocytes.

  4. drug sensitivity profiles of a set of compound mutations in ABL kinase were also presented in this study. Thus, our large scale computational study provides comprehensive sensitivity/resistance profiles of ABL mutations toward specific kinase inhibitors.

  5. High expression of MTTP (show MTTP Proteins) is associated with high carotid intima-media thickness.

  6. though our data support the previous findings that co-expression of BCR-ABL transcripts is due to the occurrence of exonic and intronic polymorphisms in the BCR gene, it also shows that the intronic polymorphism can arise without the linked exonic polymorphism. The occurrence of ABL kinase domain mutation is less frequent in Indian population.

  7. In silico three-dimensional modeling of apoptin, molecular docking experiments between apoptin model and the known structure of Bcr-Abl, and the 3D structures of SH2 domains of CrkL (show CRKL Proteins) and Bcr-Abl, were performed.

  8. The present study screened for the presence of bcr-abl transcripts in the blood of a group of healthy individuals.

  9. inhibition of c-Abl minimizes receptor recycling pathways and results in chaperone-dependent trafficking of the TfR1 (show TFRC Proteins) to the lysosome for degradation.

  10. MTP (show MT1B Proteins) Gene Variants are associated with Homozygous Familial Hypercholesterolemia.

Mouse (Murine) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. p38a (show MAPK14 Proteins) as a major substrate of c-Abl both in vitro and in vivo and c-Abl-mediated phosphorylation is critical for the dimerization of p38a (show MAPK14 Proteins).

  2. Our data show that: i) HDAC2 (show HDAC2 Proteins) levels and activity are increased in NPC (show NPC1 Proteins) neuronal models and in Npc1 (show NPC1 Proteins)(-/-) mice; ii) inhibition of c-Abl or c-Abl deficiency prevents the increase of HDAC2 (show HDAC2 Proteins) protein levels and activity in NPC (show NPC1 Proteins) neuronal models

  3. The resistance in BCR (show BCR Proteins)-ABL1 cells resulted either from the Y253H mutation in the BCR (show BCR Proteins)-ABL1 gene or incubation in increasing concentrations of imatinib.

  4. These results reveal a new pathway in the DNA damage response wherein ABL-dependent tyrosine phosphorylation of DGCR8 (show DGCR8 Proteins) stimulates the processing of selective primary miRNAs.

  5. These findings connect the EphB signaling pathway to the regulation of intestinal adenoma initiation via Abl kinase.

  6. overexpression of Id2 in primary alveolar epithelial cells promotes proliferation by inhibiting a retinoblastoma protein/c-Abl interaction leading to greater c-Abl activity.

  7. The study demonstrates a previously unrecognized mechanism that controls insulin (show INS Proteins) expression through c-Abl-regulated NKx2.2 (show Nkx2-2 Proteins) and GLUT2 (show SLC2A2 Proteins).

  8. Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.

  9. LPS-induced paxillin phosphorylation at Y31 and Y118 was mediated by c-Abl tyrosine kinase

  10. c-Abl modulates tumor cell sensitivity to antibody-dependent cellular cytotoxicity.

Caenorhabditis elegans (C. elegans) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) interaction partners

  1. MIG-13 (show DHPS Proteins)-WAVE pathway provides the major force for directional cell motility, whereas MIG-13 (show DHPS Proteins)-WASP (show WASL Proteins) partially compensates for its loss, underscoring their coordinated activities in facilitating robust cell migration.

  2. By screening candidate genes involved in Eph (show EPHA1 Proteins) signaling, we find that the Eph (show EPHA1 Proteins) kinase-independent pathway involves the ABL-1 nonreceptor tyrosine kinase (show TYRO3 Proteins) and possibly the phosphatidylinositol 3-kinase pathway

  3. The trade-off in immunological susceptibility in C. elegans is further mediated by the reciprocal activity of lys (show LYZ Proteins)-7 and the tyrosine kinase abl-1.

  4. oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 (show TP53 Proteins) and EGL-1 independent pathway; the MAPK (show MAPK1 Proteins) kinases MEK-1 (show MAP2K1 Proteins) and SEK-1 (show MAP2K4 Proteins), and the p53 (show TP53 Proteins) antagonist protein ABL-1, are essential for stress-induced germ cell apoptosis

  5. findings demonstrate that ABL-1, the C. elegans homolog of the mammalian c-Abl nonreceptor tyrosine kinase (show TYRO3 Proteins) ABL1, is required for Shigella flexneri pathogenesis in nematodes

ABL1 Protein Profile

Protein Summary

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Alternative names and synonyms associated with ABL1

  • c-abl oncogene 1, receptor tyrosine kinase (ABL1)
  • c-abl oncogene 1, non-receptor tyrosine kinase (ABL1)
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2)
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (abl2)
  • c-abl oncogene 1, non-receptor tyrosine kinase (Abl1)
  • microsomal triglyceride transfer protein (MTTP)
  • Protein ABL-1 (abl-1)
  • Abl protein
  • ABL1 protein
  • ABLL protein
  • AI325092 protein
  • bcr/abl protein
  • c-Abl protein
  • CABL protein
  • cb272 protein
  • E430008G22Rik protein
  • JTK7 protein
  • MTP protein
  • p150 protein
  • v-abl protein

Protein level used designations for ABL1

c-abl oncogene 1, receptor tyrosine kinase , v-abl Abelson murine leukemia viral oncogene homolog 1 , Abelson murine leukemia viral (v-abl) oncogene homolog 1 , v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) , tyrosine kinase ABL , Abelson murine leukemia viral (v-abl) oncogene homolog 2 , Abelson tyrosine-protein kinase 2 , arg, Abelson-related , tyrosine-protein kinase ABL2 , v-abl Abelson murine leukemia viral oncogene homolog 2 , arg tyrosine kinase , tyrosine-protein kinase ABL2-like , Abelson tyrosine-protein kinase 1 , bcr/c-abl oncogene protein , proto-oncogene c-Abl , proto-oncogene tyrosine-protein kinase ABL1 , tyrosine-protein kinase ABL1 , Abelson murine leukemia oncogene , abelson murine leukemia viral oncogene homolog 1 , p150 , v-abl Abelson murine leukemia oncogene 1 , v-abl Abelson murine leukemia viral oncogene 1 , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein large subunit

280970 Bos taurus
417181 Gallus gallus
464802 Pan troglodytes
491292 Canis lupus familiaris
395410 Gallus gallus
457552 Pan troglodytes
511845 Bos taurus
570636 Danio rerio
717037 Macaca mulatta
100348328 Oryctolagus cuniculus
100463896 Ailuropoda melanoleuca
100543723 Meleagris gallopavo
100588798 Nomascus leucogenys
25 Homo sapiens
540876 Bos taurus
11350 Mus musculus
311860 Rattus norvegicus
4547 Homo sapiens
181261 Caenorhabditis elegans
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