Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
The Arabidopsis Malectin (show MLEC ELISA Kits)-Like/LRR-RLK (show TXK ELISA Kits) IOS1 Is Critical for BAK1-Dependent and BAK1-Independent Pattern-Triggered Immunity
These findings show that BAK1 contains an additional AtRALF1 binding site, indicating that this protein may be part of a AtRALF1-containing complex as a co-receptor, and it is required for the negative regulation of cell expansion
the existence of partial redundancy between SERK3 and SERK1 as well as the promoting or repressive activity of a single coreceptor in multiple simultaneously active pathways, is reported.
The found that in an otherwise "active" BAK1 the alphaC helix is highly disordered, a hallmark of deactivation, whereas the BRI1 alphaC helix is moderately disordered and displays swinging behavior similar to numerous animal kinases.
These data suggest that BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death.
Oligogalacturonides are sensed through multiple and partially redundant perception/transduction complexes, some targeted by AvrPto, but not necessarily comprising BAK1 and BKK1.
These results suggest that pleiotropic phenotypic alterations shown in the BAK1- overexpressing transgenic plants result from the constitutive activation of SA-mediated defense responses.
The study reveals the signaling activation mechanism in floral organ abscission by IDA-induced HAE/HSL2-SERK complex formation accompanied by transphosphorylation.
Receptor like kinases (RLP)-mediated resistance and endocytosis require ligand-induced recruitment of BAK1/SERK3, reminiscent of BAK1/SERK3 interaction and subcellular fate of the FLAGELLIN (show FliC ELISA Kits) SENSING 2 (FLS2) RLK (show TXK ELISA Kits).
G protein signaling is directly activated by the pathogen-associated molecular pattern flagellin (show FliC ELISA Kits) peptide 22 through its LRR RLK (show TXK ELISA Kits), FLS2, and co-receptor BAK1.
interleukin-6 (show IL6 ELISA Kits), endothelin ET-1 (show EDN1 ELISA Kits), and apoptotic Bak and Bcl-XL (show BCL2L1 ELISA Kits) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Bak mRNA was significantly increased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis
UMI-77 enhances TRAIL-induced apoptosis by unsequestering Bim (show BCL2L11 ELISA Kits) and Bak, which provides a novel therapeutic strategy for the treatment of gliomas.
after the induction of apoptosis, Bak switches from its association with Mtx2 (show MTX2 ELISA Kits) and VDAC2 (show VDAC2 ELISA Kits) to a closer association with Mtx1 (show MTX1 ELISA Kits).
Conversion of Bim (show BCL2L11 ELISA Kits)-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
The results strongly suggest that the direct apoptosis-activation activities of Bid (show BID ELISA Kits), Bim (show BCL2L11 ELISA Kits), Puma (show BBC3 ELISA Kits), and p53 (show TP53 ELISA Kits) are not essential for activating Bax (show BAX ELISA Kits)/Bak once the anti-apoptotic Bcl-2 (show BCL2 ELISA Kits) proteins are neutralized.
Studied BAK1, SPRY4 (show SPRY4 ELISA Kits) and GAB2 (show GAB2 ELISA Kits) SNPs in pediatric germ cell tumors(GCT (show QPCT ELISA Kits)); found a variant in SPRY4 (show SPRY4 ELISA Kits) was associated with reduced risk of GCT (show QPCT ELISA Kits); a variant in BAK1 was positively associated with GCT (show QPCT ELISA Kits) with a strong estimated effect for testis tumors; and a SNP in GAB2 (show GAB2 ELISA Kits) was associated with increased risk for GCT (show QPCT ELISA Kits).
These results not only establish Bok (show BOK ELISA Kits) as a Bak- and Bax (show BAX ELISA Kits)-independent apoptosis inducer, but also suggest a potential impact of Bok (show BOK ELISA Kits) expression in ovarian cancer therapy.
The low-level constitutive production of platelets caused by the G allele of rs5745568 in BAK1 protein seems to increase the risk of bleeding in dengue infection
the expression of Bak1 was downregulated in CRC (show CALR ELISA Kits) tumor tissues and was reversely correlated with the expression of miR410, which provided further support that Bak1 was regulated by miR410.
Low expression of BAX (show BAX ELISA Kits) is associated with docetaxel resistance in gastric cancer.
Polymorphisms of KITLG (show KITLG ELISA Kits), SPRY4 (show SPRY4 ELISA Kits), and BAK1 genes in patients with testicular germ cell tumors and individuals with infertility associated with AZFc deletion of the Y chromosome
Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax (show BAX ELISA Kits)/Bak-caspase (show CASP3 ELISA Kits) signaling cascade. Adult Bax (show BAX ELISA Kits)/Bak mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.
The authors show that Bak is activated and that activated Bak is bound to p53 (show TP53 ELISA Kits) during reovirus encephalitis.
Pancreatic beta-Cell Death due to Pdx-1 (show PDX1 ELISA Kits) Deficiency Requires Multi-BH Domain Protein Bax (show BAX ELISA Kits) but Not Bak.
lipid profile in the absence of the proapoptotic proteins BAX (show BAX ELISA Kits) and BAK in mouse embryonic fibroblasts
alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.
BAX (show BAX ELISA Kits) and BAK have a nonapoptotic role in eicosanoid metabolism in inflammation.
Puma (show BBC3 ELISA Kits) is the major mediator of virus-induced Bax (show BAX ELISA Kits)/Bak activation and mitochondrial membrane permeabilization induction.
Motifs of VDAC2 (show VDAC2 ELISA Kits) required for mitochondrial Bak import and tBid-induced apoptosis.
dual ablation of Bax (show BAX ELISA Kits) and Bak suppressed ureteral obstruction induced inflammation and kidney fibrosis with decreased tubular cell cycle arrest
regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 (show CASP9 ELISA Kits) activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
BCL2-like 7 protein
, apoptosis regulator BAK
, bcl-2 homologous antagonist/killer
, bcl-2-like protein 7
, pro-apoptotic protein BAK
, Bcl2 homologous antagonist/killer
, Bcl-2-like 7