Browse our BAK1 Proteins (BAK1)

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BCL2-Antagonist/killer 1 Proteins (BAK1)
On are 4 BCL2-Antagonist/killer 1 (BAK1) Proteins from 2 different suppliers available. Additionally we are shipping BAK1 Antibodies (187) and BAK1 Kits (33) and many more products for this protein. A total of 250 BAK1 products are currently listed.
list all proteins Gene Name GeneID UniProt
BAK1 578 Q16611
BAK1 12018  
Rat BAK1 BAK1 116502  

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BAK1 Proteins (BAK1) by Origin

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Top referenced BAK1 Proteins

  1. Human BAK1 Protein expressed in Wheat germ - ABIN1346390 : Lindner, Concannon, Boukes, Cannon, Llambi, Ryan, Boland, Kehoe, McNamara, Murray, Kay, Hector, Green, Huber, Prehn: Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy. in Cancer research 2013 (PubMed)

More Proteins for BAK1 Interaction Partners

Arabidopsis thaliana BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. The found that in an otherwise "active" BAK1 the alphaC helix is highly disordered, a hallmark of deactivation, whereas the BRI1 alphaC helix is moderately disordered and displays swinging behavior similar to numerous animal kinases.

  2. These data suggest that BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death.

  3. Oligogalacturonides are sensed through multiple and partially redundant perception/transduction complexes, some targeted by AvrPto, but not necessarily comprising BAK1 and BKK1.

  4. These results suggest that pleiotropic phenotypic alterations shown in the BAK1- overexpressing transgenic plants result from the constitutive activation of SA-mediated defense responses.

  5. The study reveals the signaling activation mechanism in floral organ abscission by IDA-induced HAE/HSL2-SERK complex formation accompanied by transphosphorylation.

  6. Receptor like kinases (RLP)-mediated resistance and endocytosis require ligand-induced recruitment of BAK1/SERK3, reminiscent of BAK1/SERK3 interaction and subcellular fate of the FLAGELLIN (show FliC Proteins) SENSING 2 (FLS2) RLK (show TXK Proteins).

  7. G protein signaling is directly activated by the pathogen-associated molecular pattern flagellin (show FliC Proteins) peptide 22 through its LRR RLK (show TXK Proteins), FLS2, and co-receptor BAK1.

  8. BAK1 disruption stimulates the release of PROPEP3, produced in response to Pep application and during pathogen challenge, and renders PEPRs necessary for basal resistance.

  9. mutation of suppressor of BIR1 (show KCNJ6 Proteins)-1, which encodes an emerging positive regulator of transmembrane receptors in plants, suppressed the effects of BAK1 overexpression.

  10. SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin (show FliC Proteins) signaling.

Pig (Porcine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. interleukin-6 (show IL6 Proteins), endothelin ET-1 (show EDN1 Proteins), and apoptotic Bak and Bcl-XL (show BCL2L1 Proteins) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bak mRNA was significantly increased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

Human BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. Studied BAK1, SPRY4 (show SPRY4 Proteins) and GAB2 (show GAB2 Proteins) SNPs in pediatric germ cell tumors(GCT (show QPCT Proteins)); found a variant in SPRY4 (show SPRY4 Proteins) was associated with reduced risk of GCT (show QPCT Proteins); a variant in BAK1 was positively associated with GCT (show QPCT Proteins) with a strong estimated effect for testis tumors; and a SNP in GAB2 (show GAB2 Proteins) was associated with increased risk for GCT (show QPCT Proteins).

  2. These results not only establish Bok (show BOK Proteins) as a Bak- and Bax (show BAX Proteins)-independent apoptosis inducer, but also suggest a potential impact of Bok (show BOK Proteins) expression in ovarian cancer therapy.

  3. The low-level constitutive production of platelets caused by the G allele of rs5745568 in BAK1 protein seems to increase the risk of bleeding in dengue infection

  4. the expression of Bak1 was downregulated in CRC (show CALR Proteins) tumor tissues and was reversely correlated with the expression of miR410, which provided further support that Bak1 was regulated by miR410.

  5. Low expression of BAX (show BAX Proteins) is associated with docetaxel resistance in gastric cancer.

  6. Polymorphisms of KITLG (show KITLG Proteins), SPRY4 (show SPRY4 Proteins), and BAK1 genes in patients with testicular germ cell tumors and individuals with infertility associated with AZFc deletion of the Y chromosome

  7. Different selenium concentrations had varying effects on BAK1 and APAF1 (show APAF1 Proteins) levels. APAF1 (show APAF1 Proteins) may play an important role in the pathogenesis of KBD

  8. Findings argue for auto-activation of Bak in the absence of anti-apoptotic Bcl-2 (show BCL2 Proteins) proteins and provide evidence of profound differences in the activation of Bax (show BAX Proteins) and Bak.

  9. LTX-315 kills cancer cells through Bax (show BAX Proteins)/Bak-regulated mitochondrial membrane permeabilization

  10. E6 proteins of human papillomavirus types 6 and 11 are able to protect keratinocytes from apoptosis via Bak degradation.

Mouse (Murine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax (show BAX Proteins)/Bak-caspase (show CASP3 Proteins) signaling cascade. Adult Bax (show BAX Proteins)/Bak mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.

  2. The authors show that Bak is activated and that activated Bak is bound to p53 (show TP53 Proteins) during reovirus encephalitis.

  3. Pancreatic beta-Cell Death due to Pdx-1 (show PDX1 Proteins) Deficiency Requires Multi-BH Domain Protein Bax (show BAX Proteins) but Not Bak.

  4. lipid profile in the absence of the proapoptotic proteins BAX (show BAX Proteins) and BAK in mouse embryonic fibroblasts

  5. alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.

  6. BAX (show BAX Proteins) and BAK have a nonapoptotic role in eicosanoid metabolism in inflammation.

  7. Puma (show BBC3 Proteins) is the major mediator of virus-induced Bax (show BAX Proteins)/Bak activation and mitochondrial membrane permeabilization induction.

  8. Motifs of VDAC2 (show VDAC2 Proteins) required for mitochondrial Bak import and tBid-induced apoptosis.

  9. dual ablation of Bax (show BAX Proteins) and Bak suppressed ureteral obstruction induced inflammation and kidney fibrosis with decreased tubular cell cycle arrest

  10. bak therefore regulates gastric epithelial cell apoptosis, proliferation, differentiation, mucosal thickness, and susceptibility to gastric atrophy and dysplasia following H. felis infection

Cow (Bovine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 (show CASP9 Proteins) activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids

BAK1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Alternative names and synonyms associated with BAK1

  • Leu-rich receptor Serine/threonine protein kinase BAK1 (BAK1)
  • Bak protein (BAK)
  • BCL2-antagonist/killer 1 (BAK1)
  • BCL2-antagonist/killer 1 (Bak1)
  • BCL2-antagonist/killer 1-like (LOC100342046)
  • ATBAK1 protein
  • ATSERK3 protein
  • Bak protein
  • BAK-LIKE protein
  • Bak1 protein
  • BCL2L7 protein
  • BRI1-associated receptor kinase protein
  • CDN1 protein
  • ELG protein
  • ELONGATED protein
  • F17M5.190 protein
  • F17M5_190 protein
  • N-Bak protein
  • N-BAK1 protein
  • RKS10 protein
  • SERK3 protein

Protein level used designations for BAK1

BCL2-like 7 protein , apoptosis regulator BAK , bcl-2 homologous antagonist/killer , bcl-2-like protein 7 , bcl2-L-7 , pro-apoptotic protein BAK , Bcl2 homologous antagonist/killer , Bcl-2-like 7

829480 Arabidopsis thaliana
397543 Sus scrofa
578 Homo sapiens
12018 Mus musculus
116502 Rattus norvegicus
100734553 Cavia porcellus
481744 Canis lupus familiaris
514090 Bos taurus
419912 Gallus gallus
100342046 Oryctolagus cuniculus
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