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Browse our BAK1 Proteins (BAK1)

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BCL2-Antagonist/killer 1 Proteins (BAK1)
On are 4 BCL2-Antagonist/killer 1 (BAK1) Proteins from 2 different suppliers available. Additionally we are shipping BAK1 Antibodies (167) and BAK1 Kits (40) and many more products for this protein. A total of 238 BAK1 products are currently listed.
list all proteins Gene Name GeneID UniProt
BAK1 578 Q16611
BAK1 12018  
Rat BAK1 BAK1 116502  

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BAK1 Proteins (BAK1) by Origin

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Top referenced BAK1 Proteins

  1. Human BAK1 Protein expressed in Wheat germ - ABIN1346390 : Lindner, Concannon, Boukes, Cannon, Llambi, Ryan, Boland, Kehoe, McNamara, Murray, Kay, Hector, Green, Huber, Prehn: Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy. in Cancer research 2013 (PubMed)

More Proteins for BAK1 Interaction Partners

Arabidopsis thaliana BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. BAK1 disruption stimulates the release of PROPEP3, produced in response to Pep application and during pathogen challenge, and renders PEPRs necessary for basal resistance.

  2. mutation of suppressor of BIR1 (show KCNJ6 Proteins)-1, which encodes an emerging positive regulator of transmembrane receptors in plants, suppressed the effects of BAK1 overexpression.

  3. SERK1 or SERK2 extracellular domains are essential for SERK function in male sporogenesis, while the SERK3 extracellular and cytoplasmic domains are essential for SERK3 activity in brassinosteroid and flagellin (show FliC Proteins) signaling.

  4. Data indicate protein kinases FLS2 and BAK1 contribute to autoimmune signaling in ACCELERATED CELL DEATH6 (ACD6 (show EHMT2 Proteins)) L591F amino acid substitution.

  5. Arabidopsis plants expressing FLS2 with the Q530A+Q627A double mutation were impaired both in detectable interaction with BAK1 and in FLS2-mediated responses, lending overall support to current models of FLS2 structure and function.

  6. Using MALDI-TOF (show FEZF2 Proteins) MS, we identified Cys353, Cys374 and Cys408 as potential sites of glutathionylation on the BAK1 cytoplasmic domain and directed mutagenesis suggests that Cys353 and Cys408 are major sites of GRXC2-mediated glutathionylation.

  7. Genetic analysis of brl1 brl3 bak1-3 triple mutants revealed that BAK1, BRL1, and BRL3 signaling modulate root growth and development by contributing to the cellular activities of provascular and quiescent center cells.

  8. study first mapped the phosphorylation patterns of BAK1 associated with four RLK partners (BRI1, FLS2, EFR and BIK1

  9. The substrate specificity of the signaling receptor-like kinases, CERK1 and BAK1, may determine the preference of downstream receptor-like cytoplasmic kinases (RLCKs).

  10. The results indicate that the extracellular domains of BRI1 and BAK1 interact with each other in a BL- and pH-dependent manner.

Pig (Porcine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. interleukin-6 (show IL6 Proteins), endothelin ET-1 (show EDN1 Proteins), and apoptotic Bak and Bcl-XL (show BCL2L1 Proteins) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bak mRNA was significantly increased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

Human BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. Findings argue for auto-activation of Bak in the absence of anti-apoptotic Bcl-2 (show BCL2 Proteins) proteins and provide evidence of profound differences in the activation of Bax (show BAX Proteins) and Bak.

  2. LTX-315 kills cancer cells through Bax (show BAX Proteins)/Bak-regulated mitochondrial membrane permeabilization

  3. E6 proteins of human papillomavirus types 6 and 11 are able to protect keratinocytes from apoptosis via Bak degradation.

  4. A Novel Naphthalimide Compound Restores p53 (show TP53 Proteins) Function in Non-small Cell Lung Cancer by Reorganizing the Bak.Bcl-xl Complex and Triggering Transcriptional Regulation.

  5. Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains.

  6. Low expression of pro-apoptotic Bak protein in in Waldenstrom macroglobulinemia.

  7. Report shows that high Bak expression is associated with the favorable overall survival rates of breast cancer patients.

  8. alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.

  9. the BH3 mimetic ABT-737 induces autophagy through a BAX (show BAX Proteins) and BAK1-independent mechanism that likely involves disruption of BECN1 (show BECN1 Proteins) binding to antiapoptotic BCL2 (show BCL2 Proteins) family members

  10. Data with full-length proteins indicate that most BH3-only (show BBC3 Proteins) proteins can directly activate both Bak and Bax (show BAX Proteins).

Mouse (Murine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. lipid profile in the absence of the proapoptotic proteins BAX (show BAX Proteins) and BAK in mouse embryonic fibroblasts

  2. alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.

  3. BAX (show BAX Proteins) and BAK have a nonapoptotic role in eicosanoid metabolism in inflammation.

  4. Puma (show BBC3 Proteins) is the major mediator of virus-induced Bax (show BAX Proteins)/Bak activation and mitochondrial membrane permeabilization induction.

  5. Motifs of VDAC2 (show VDAC2 Proteins) required for mitochondrial Bak import and tBid-induced apoptosis.

  6. dual ablation of Bax (show BAX Proteins) and Bak suppressed ureteral obstruction induced inflammation and kidney fibrosis with decreased tubular cell cycle arrest

  7. bak therefore regulates gastric epithelial cell apoptosis, proliferation, differentiation, mucosal thickness, and susceptibility to gastric atrophy and dysplasia following H. felis infection

  8. Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53 (show TP53 Proteins)-independent necrosis via the mitochondria-associated pathway involving Bax (show BAX Proteins) and Bak activation

  9. MCL1 (show MCL1 Proteins), but not that of BAK, forms stable heterodimeric complexes with cBID in a manner adjustable by membrane cardiolipin content and curvature degree.

  10. data predict that the MPTP (show PTPN2 Proteins) is an inner membrane regulated process, although in the absence of Bax (show BAX Proteins)/Bak the outer membrane resists swelling and prevents organelle rupture to prevent cell death

Cow (Bovine) BCL2-Antagonist/killer 1 (BAK1) interaction partners

  1. regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 (show CASP9 Proteins) activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids

BAK1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Alternative names and synonyms associated with BAK1

  • Leu-rich receptor Serine/threonine protein kinase BAK1 (BAK1)
  • Bak protein (BAK)
  • BCL2-antagonist/killer 1 (BAK1)
  • BCL2-antagonist/killer 1 (Bak1)
  • BCL2-antagonist/killer 1-like (LOC100342046)
  • ATBAK1 protein
  • ATSERK3 protein
  • Bak protein
  • BAK-LIKE protein
  • Bak1 protein
  • BCL2L7 protein
  • BRI1-associated receptor kinase protein
  • CDN1 protein
  • ELG protein
  • ELONGATED protein
  • F17M5.190 protein
  • F17M5_190 protein
  • N-Bak protein
  • N-BAK1 protein
  • RKS10 protein
  • SERK3 protein

Protein level used designations for BAK1

BCL2-like 7 protein , apoptosis regulator BAK , bcl-2 homologous antagonist/killer , bcl-2-like protein 7 , bcl2-L-7 , pro-apoptotic protein BAK , Bcl2 homologous antagonist/killer , Bcl-2-like 7

829480 Arabidopsis thaliana
397543 Sus scrofa
578 Homo sapiens
12018 Mus musculus
116502 Rattus norvegicus
100734553 Cavia porcellus
481744 Canis lupus familiaris
514090 Bos taurus
419912 Gallus gallus
100342046 Oryctolagus cuniculus
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