Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
The Arabidopsis Malectin (show MLEC Proteins)-Like/LRR-RLK (show TXK Proteins) IOS1 Is Critical for BAK1-Dependent and BAK1-Independent Pattern-Triggered Immunity
These findings show that BAK1 contains an additional AtRALF1 binding site, indicating that this protein may be part of a AtRALF1-containing complex as a co-receptor, and it is required for the negative regulation of cell expansion
the existence of partial redundancy between SERK3 and SERK1 as well as the promoting or repressive activity of a single coreceptor in multiple simultaneously active pathways, is reported.
The found that in an otherwise "active" BAK1 the alphaC helix is highly disordered, a hallmark of deactivation, whereas the BRI1 alphaC helix is moderately disordered and displays swinging behavior similar to numerous animal kinases.
These data suggest that BIK1 cooperates with BAK1 to regulate constitutive immunity and cell death.
Oligogalacturonides are sensed through multiple and partially redundant perception/transduction complexes, some targeted by AvrPto, but not necessarily comprising BAK1 and BKK1.
These results suggest that pleiotropic phenotypic alterations shown in the BAK1- overexpressing transgenic plants result from the constitutive activation of SA-mediated defense responses.
The study reveals the signaling activation mechanism in floral organ abscission by IDA-induced HAE/HSL2-SERK complex formation accompanied by transphosphorylation.
Receptor like kinases (RLP)-mediated resistance and endocytosis require ligand-induced recruitment of BAK1/SERK3, reminiscent of BAK1/SERK3 interaction and subcellular fate of the FLAGELLIN (show FliC Proteins) SENSING 2 (FLS2) RLK (show TXK Proteins).
G protein signaling is directly activated by the pathogen-associated molecular pattern flagellin (show FliC Proteins) peptide 22 through its LRR RLK (show TXK Proteins), FLS2, and co-receptor BAK1.
interleukin-6 (show IL6 Proteins), endothelin ET-1 (show EDN1 Proteins), and apoptotic Bak and Bcl-XL (show BCL2L1 Proteins) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Bak mRNA was significantly increased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis
The results strongly suggest that the direct apoptosis-activation activities of Bid (show BID Proteins), Bim (show BCL2L11 Proteins), Puma (show BBC3 Proteins), and p53 (show TP53 Proteins) are not essential for activating Bax (show BAX Proteins)/Bak once the anti-apoptotic Bcl-2 (show BCL2 Proteins) proteins are neutralized.
Studied BAK1, SPRY4 (show SPRY4 Proteins) and GAB2 (show GAB2 Proteins) SNPs in pediatric germ cell tumors(GCT (show QPCT Proteins)); found a variant in SPRY4 (show SPRY4 Proteins) was associated with reduced risk of GCT (show QPCT Proteins); a variant in BAK1 was positively associated with GCT (show QPCT Proteins) with a strong estimated effect for testis tumors; and a SNP in GAB2 (show GAB2 Proteins) was associated with increased risk for GCT (show QPCT Proteins).
These results not only establish Bok (show BOK Proteins) as a Bak- and Bax (show BAX Proteins)-independent apoptosis inducer, but also suggest a potential impact of Bok (show BOK Proteins) expression in ovarian cancer therapy.
The low-level constitutive production of platelets caused by the G allele of rs5745568 in BAK1 protein seems to increase the risk of bleeding in dengue infection
the expression of Bak1 was downregulated in CRC (show CALR Proteins) tumor tissues and was reversely correlated with the expression of miR410, which provided further support that Bak1 was regulated by miR410.
Low expression of BAX (show BAX Proteins) is associated with docetaxel resistance in gastric cancer.
Polymorphisms of KITLG (show KITLG Proteins), SPRY4 (show SPRY4 Proteins), and BAK1 genes in patients with testicular germ cell tumors and individuals with infertility associated with AZFc deletion of the Y chromosome
Different selenium concentrations had varying effects on BAK1 and APAF1 (show APAF1 Proteins) levels. APAF1 (show APAF1 Proteins) may play an important role in the pathogenesis of KBD
Findings argue for auto-activation of Bak in the absence of anti-apoptotic Bcl-2 (show BCL2 Proteins) proteins and provide evidence of profound differences in the activation of Bax (show BAX Proteins) and Bak.
LTX-315 kills cancer cells through Bax (show BAX Proteins)/Bak-regulated mitochondrial membrane permeabilization
Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax (show BAX Proteins)/Bak-caspase (show CASP3 Proteins) signaling cascade. Adult Bax (show BAX Proteins)/Bak mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.
The authors show that Bak is activated and that activated Bak is bound to p53 (show TP53 Proteins) during reovirus encephalitis.
Pancreatic beta-Cell Death due to Pdx-1 (show PDX1 Proteins) Deficiency Requires Multi-BH Domain Protein Bax (show BAX Proteins) but Not Bak.
lipid profile in the absence of the proapoptotic proteins BAX (show BAX Proteins) and BAK in mouse embryonic fibroblasts
alpha1 dissociation is a key step in unfolding Bak into three major components, the N terminus, the core (alpha2-alpha5) and the latch (alpha6-alpha8) that is required for apoptosis.
BAX (show BAX Proteins) and BAK have a nonapoptotic role in eicosanoid metabolism in inflammation.
Puma (show BBC3 Proteins) is the major mediator of virus-induced Bax (show BAX Proteins)/Bak activation and mitochondrial membrane permeabilization induction.
Motifs of VDAC2 (show VDAC2 Proteins) required for mitochondrial Bak import and tBid-induced apoptosis.
dual ablation of Bax (show BAX Proteins) and Bak suppressed ureteral obstruction induced inflammation and kidney fibrosis with decreased tubular cell cycle arrest
bak therefore regulates gastric epithelial cell apoptosis, proliferation, differentiation, mucosal thickness, and susceptibility to gastric atrophy and dysplasia following H. felis infection
regulation of A1 and Bak contribute to mitochondrial membrane stability, reduced caspase-9 (show CASP9 Proteins) activity, and delayed apoptosis in bovine neutrophils exposed to glucocorticoids
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
BCL2-like 7 protein
, apoptosis regulator BAK
, bcl-2 homologous antagonist/killer
, bcl-2-like protein 7
, pro-apoptotic protein BAK
, Bcl2 homologous antagonist/killer
, Bcl-2-like 7